Abstract Transition-metal-catalysed, non-enzymatic transformations of C–H and C= C bonds
to C–N bonds through nitrene transfer (NT) are powerful synthetic tools to prepare valuable …

The introduction of nitrogen atoms into small molecules is of fundamental importance and it
is vital that ever more efficient and selective methods for achieving this are developed. With …

An asymmetric intramolecular spiro-amination to high steric hindering α-C–H bond of 1, 3-
dicarbonyl via nitrene transfer using inactive aryl azides has been carried out by developing …

Propargyl amines are versatile synthetic intermediates with numerous applications in the
pharmaceutical industry. An attractive strategy for efficient preparation of these compounds …

Racemization is considered to be an intrinsic stereochemical feature of free radical
chemistry as can be seen in traditional radical halogenation reactions of optically active …

Directed evolution of heme proteins has opened access to new‐to‐nature enzymatic activity
that can be harnessed to tackle synthetic challenges. Among these, reactions resulting from …

Controlling regio-and enantioselectivity in C–H functionalization reactions is of paramount
importance due to their versatile synthetic utilities. Herein, we describe a new approach for …

Described herein is the Ir-catalyzed enantioselective access to chiral spirolactam products
via the nitrenoid transfer to aromatic ipso-carbons. The key strategy for precise stereocontrol …

Nitrene transfer reactions are powerful tools in synthetic organic chemistry. In recent years,
transition-metal catalyzed nitrene transfer reactions with carbamates as the nitrene …

Engineered metalloenzymes represent promising catalysts for stereoselective C–H
functionalization reactions. Recently, P450 enzymes have been evolved to allow for new-to …