N‐Heterocyclic Carbene Catalysis via Azolium Dienolates: An Efficient Strategy for Remote Enantioselective Functionalizations

XY Chen, Q Liu, P Chauhan… - Angewandte Chemie …, 2018 - Wiley Online Library
N‐heterocyclic carbene (NHC) catalysis has emerged as a powerful strategy in organic
synthesis. In recent years a number of reviews have been published on NHC‐catalyzed …

New developments of the principle of vinylogy as applied to π-extended enolate-type donor systems

C Curti, L Battistini, A Sartori, F Zanardi - Chemical reviews, 2020 - ACS Publications
The principle of vinylogy states that the electronic effects of a functional group in a molecule
are possibly transmitted to a distal position through interposed conjugated multiple bonds …

Generation of azolium dienolates as versatile nucleophilic synthons via N-heterocyclic carbene catalysis

J Gao, J Feng, D Du - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
N-Heterocyclic carbene (NHC) organocatalysis has emerged as a powerful tool in the field
of modern organic synthesis especially in asymmetric construction of various cyclic …

[HTML][HTML] Asymmetric reactions of N-heterocyclic carbene (NHC)-based chiral acyl azoliums and azolium enolates

C Zhao, SA Blaszczyk, J Wang - Green Synthesis and Catalysis, 2021 - Elsevier
N-Heterocyclic carbene (NHC) organocatalysis has been recognized as a powerful synthetic
strategy for the construction of a wide variety of medicinally and biologically important …

Asymmetric annulations based on cycloisomerization of cyclopropyl tethered allenyl ketones by bimetallic relay catalysis

J He, W Liu, J Zhang, Z Zhong, L Lin, X Feng - Science China Chemistry, 2023 - Springer
The diastereo-and enantioselective tandem cycloisomerization/[4+ 2]-cycloaddition reaction
of cyclopropyl tethered allenyl ketones with α, β-unsaturated carbonyl compounds was …

Catalytic System‐Controlled Divergent Reaction Strategies for the Construction of Diversified Spiropyrazolone Skeletons from Pyrazolidinones and Diazopyrazolones

F Fang, S Hu, C Li, Q Wang, R Wang… - Angewandte Chemie …, 2021 - Wiley Online Library
A catalytic system‐controlled divergent reaction strategy was here reported to construct four
types of intriguing spiroheterocyclic skeletons from simple and readily available starting …

Recent advances of N-heterocyclic carbenes in the applications of constructing carbo-and heterocyclic frameworks with potential biological activity

MM Li, X Chen, Y Deng, J Lu - RSC advances, 2021 - pubs.rsc.org
In recent years, N-heterocyclic carbenes (NHCs) have established themselves as a
masterful and promising type of organocatalyst for the speedy construction of medicinally …

N‐Heterocyclic Carbene Catalyzed [4+ 2] Annulation of Enals via a Double Vinylogous Michael Addition: Asymmetric Synthesis of 3, 5‐Diaryl Cyclohexenones

XY Chen, Q Liu, P Chauhan, S Li… - Angewandte …, 2017 - Wiley Online Library
A strategy for the N‐heterocyclic carbene (NHC) catalyzed asymmetric synthesis of 3, 5‐
diaryl substituted cyclohexenones has been developed via oxidative [4+ 2] annulation of …

Recent Advances in the Synthesis of Spiroheterocycles via N-Heterocyclic Carbene Organocatalysis

Y Liu, X Zhang, R Zeng, Y Zhang, QS Dai, HJ Leng… - Molecules, 2017 - mdpi.com
Spiroheterocycles are regarded as a privileged framework because of their wide distribution
in various natural products and synthetic molecules and promising bioactivities. This review …

Enantioselective (4+ 2) Annulation of Donor–Acceptor Cyclobutanes by N‐Heterocyclic Carbene Catalysis

A Levens, A Ametovski, DW Lupton - Angewandte Chemie, 2016 - Wiley Online Library
Herein we report the enantioselective (4+ 2) annulation of donor–acceptor cyclobutanes and
unsaturated acyl fluorides using N‐heterocyclic carbene catalysis. The reaction allows a 3 …