Owing to their unique properties, propargylic alcohols have been recognized as one of the
most attractive synthons in the field of organic synthesis. Particularly, with the aid of auxiliary …

An axially chiral indolyl-pyrroloindole scaffold, a new member of axially chiral indole-based
scaffolds, has been designed, and the catalytic asymmetric construction of this scaffold has …

Organocatalytic enantioselective construction of chiral spiro N, N-acetal carbon
stereocenters and axially chiral 3-arylindoles has been achieved via a chiral phosphoric …

A novel chiral phosphoric acid-catalyzed tandem regioselective 1, 6-addition/double
intramolecular nucleophilic addition annulation of the propargylic 3-methyleneindoles in situ …

Asymmetric cycloaddition/annulation reactions have contributed greatly to the synthesis of a
variety of novel cyclic compounds used in organic synthesis, natural product synthesis …

A chiral Brønsted acid catalyzed asymmetric aza-Piancatelli rearrangement of 3-furyl-3-
hydroxyisoindolinones with anilines has been developed, enabling the divergent …

With the aid of chiral phosphoric acid, enantioselective 1, 6-addition of tryptamines to in situ
formed alkynyl 7-methylene-7H-indoles from tertiary α-(7-indolyl) methanols has been …

Phthalimide and N-phenylphthalimide smoothly condense with di-p-tolyl ether in triflic acid
(CF3SO3H, TfOH) to obtain the corresponding spiro [isoindoline-1, 9′-xanthen]-3-ones …

An enantioselective copper-catalyzed 1, 2-arylboration reaction of enamines has been
developed by employing (R)-xyl-BINAP as a chiral ligand. A number of chiral borate …

Developed herein is an enantioselective Friedel–Crafts alkylation reaction of N-unprotected
alkynyl trifluoromethyl ketimines with pyrroles catalyzed by chiral phosphoric acid to furnish …