Genomic regulatory networks and animal development

A Stathopoulos, M Levine - Developmental cell, 2005 - cell.com
The synthesis of gene expression data and cis-regulatory analysis permits the elucidation of
genomic regulatory networks. These networks provide a direct visualization of the functional …

Distribution of serotonin (5-HT) and its receptors in the insect brain with focus on the mushroom bodies. Lessons from Drosophila melanogaster and Apis mellifera

W Blenau, M Thamm - Arthropod structure & development, 2011 - Elsevier
The biogenic amine serotonin (5-hydroxytryptamine, 5-HT) plays a key role in regulating and
modulating various physiological and behavioral processes in both protostomes and …

Regulation of epithelial morphogenesis by the G protein–coupled receptor Mist and its ligand Fog

AJ Manning, KA Peters, M Peifer, SL Rogers - Science signaling, 2013 - science.org
Epithelial morphogenesis is essential for shaping organs and tissues and for establishment
of the three embryonic germ layers during gastrulation. Studies of gastrulation in Drosophila …

A resource for manipulating gene expression and analyzing cis-regulatory modules in the Drosophila CNS

L Manning, ES Heckscher, MD Purice, J Roberts… - Cell reports, 2012 - cell.com
Here, we describe the embryonic central nervous system expression of 5,000 GAL4 lines
made using molecularly defined cis-regulatory DNA inserted into a single attP genomic …

A Drosophila glial cell atlas reveals a mismatch between transcriptional and morphological diversity

I Lago-Baldaia, M Cooper, A Seroka, C Trivedi… - PLoS …, 2023 - journals.plos.org
Morphology is a defining feature of neuronal identity. Like neurons, glia display diverse
morphologies, both across and within glial classes, but are also known to be …

Nonvesicular release of glutamate by glial xCT transporters suppresses glutamate receptor clustering in vivo

H Augustin, Y Grosjean, K Chen, Q Sheng… - Journal of …, 2007 - Soc Neuroscience
We hypothesized that cystine/glutamate transporters (xCTs) might be critical regulators of
ambient extracellular glutamate levels in the nervous system and that misregulation of this …

Specialized Cortex Glial Cells Accumulate Lipid Droplets in Drosophila melanogaster

V Kis, B Barti, M Lippai, M Sass - PLoS One, 2015 - journals.plos.org
Lipid droplets (LDs) are common organelles of the majority of eukaryotic cell types. Their
biological significance has been extensively studied in mammalian liver cells and white …

Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission

YC Chen, YQ Lin, S Banerjee, K Venken… - Journal of …, 2012 - Soc Neuroscience
Trans-synaptic adhesion between Neurexins (Nrxs) and Neuroligins (Nlgs) is thought to be
required for proper synapse organization and modulation, and mutations in several human …

Patterns of chromatin accessibility along the anterior-posterior axis in the early Drosophila embryo

JE Haines, MB Eisen - PLoS genetics, 2018 - journals.plos.org
As the Drosophila embryo transitions from the use of maternal RNAs to zygotic transcription,
domains of open chromatin, with relatively low nucleosome density and specific histone …

Drosophila Neurexin IV stabilizes neuron-glia interactions at the CNS midline by binding to Wrapper

T Stork, S Thomas, F Rodrigues, M Silies, E Naffin… - 2009 - journals.biologists.com
Ensheathment of axons by glial membranes is a key feature of complex nervous systems
ensuring the separation of single axons or axonal fascicles. Nevertheless, the molecules …