Markers predicting progression of human immunodeficiency virus-related disease

CM Tsoukas, NF Bernard - Clinical Microbiology Reviews, 1994 - Am Soc Microbiol
Human immunodeficiency virus (HIV) interacts with the immune system throughout the
course of infection. For most of the disease process, HIV activates the immune system, and …

Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4

SS Rhee, JW Marsh - Journal of virology, 1994 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) Nef is a myristylated protein with a relative
molecular mass of 27 kDa, is localized to the cytoplasmic surfaces of cellular membranes …

From negative factor to a critical role in virus pathogenesis: the changing fortunes of Nef

M Harris - Journal of general virology, 1996 - microbiologyresearch.org
The net gene is unique to the primate lentiviruses. Over the last 5 years it has become clear
that nefplays a key role in the pathogenesis of AIDS and this has led to a resurgence in …

Antibodies to retroviral proteins in autoimmune connective tissue disease. Relation to clinical manifestations and ribonucleoprotein autoantibodies

A Ranki, P Kurki, S Riepponen… - Arthritis & Rheumatism …, 1992 - Wiley Online Library
Objective. To study the relationship between antibodies that recognize human retroviral
proteins and the presence of clinical features and ribonucleoprotein antibodies in patients …

Human bites and the risk of human immunodeficiency virus transmission

IA Pretty, GS Anderson, DJ Sweet - The American journal of …, 1999 - journals.lww.com
The risk of human immunodeficiency virus (HIV) transmission following a bite injury is
important to many groups of people. The first are those who are likely to be bitten as an …

The numerous effector functions of Nef

JW Marsh - Archives of biochemistry and biophysics, 1999 - Elsevier
Nef almost seems like an afterthought. First, for viral replication, expression of Nef is entirely
dispensable. In fact, some of the earliest HIV isolates lacked a functional Nef (1). Second …

Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1.

EF Terwilliger, E Langhoff, D Gabuzda… - Proceedings of the …, 1991 - National Acad Sciences
The effects of the viral gene nef on human immunodeficiency virus type 1 (HIV-1) replication
in culture were investigated using nef alleles of the HIV-1 IIIB and ELI strains. The results …

Nucleotide and amino acid homology between the human thyrotropin receptor and the HIV-1 Nef protein: identification and functional analysis

HB Burch, EV Nagy, YG Lukes, WY Cai… - Biochemical and …, 1991 - Elsevier
A comparison of the nucleotide sequence of the human thyrotropin receptor (hTSH-R) with
that of HIV-1 revealed 61% homology between a 161 base pair region encoding a unique …

Antigenic epitopes of NEF proteins from different HIV-1 strains as recognized by sera from patients with manifest and latent HIV infection

FO Gombert, W Blecha, M Tähtinen, A Ranki, S Pfeifer… - Virology, 1990 - Elsevier
Human immunodeficiency virus (HIV) infection that generally causes a strong antibody
response toward HIV may sometimes occur in a latent form, characterized by seronegativity …

Epitopes of the HIV-1-Negative Factor (nef) Reactive with Murine Monoclonal Antibodies and Human HIV-1-Positive Sera

T SCHNEIDER, HP HARTHUS… - AIDS research and …, 1991 - liebertpub.com
Murine monoclonal antibodies (MAbs) raised against a recombinant nef protein fragment of
human immunodeficiency virus type 1 (HIV-1) strain BH10 were characterized by an epitope …