Covering: January to December 2021 This review covers the literature published in 2021 for
marine natural products (MNPs), with 736 citations (724 for the period January to December …

Covering 1972 to 2021 Malaria remains a significant public health problem in some regions
of the world. The great efforts to control malaria have been severely compromised due to the …

The ultrasonic energy has been revisited and applied for the synthesis of bioactive
molecules in a short time and green method. These compounds can exhibit anticancer …

Isocoumarins, isomeric to comarins which act as effective carbonic anhydrase (CA, EC 4.2.
1.1) inhibitors, were investigated for the first time as inhibitors of this enzyme. A series of 3 …

Parasitic diseases still threaten human health. At present, a number of parasites have
developed drug resistance, and it is urgent to find new and effective antiparasitic drugs. As a …

Coumarin is a versatile scaffold with outstanding biological potential and played a key role
in the field of medicine. The benzopyran-2-one ring bearing heterocycles are known for …

Substituted coumarins are a very large family of naturally occurring compounds, and
substituted coumarins are versatile scaffolds for the development of medicinally active …

Marine natural products (MNPs) are valuable resources for drug development. To date, 17
drugs from marine sources are in clinical use, and 33 pharmaceutical compounds are in …

Six new isocoumarin derivative talaromarins AF (1–6), along with 17 known analogues (7–
23), were isolated from the mangrove-derived fungus Talaromyces flavus (Eurotiales …

Seven novel isocoumarins, prunolactones AG (1–7), featuring an unusual 6/6/6/6/6
spiropentacyclic skeleton, together with two biosynthetic precursors phomopsilactone (8) …