[HTML][HTML] Hydrogels in drug delivery: Progress and challenges

TR Hoare, DS Kohane - polymer, 2008 - Elsevier
There has been considerable progress in recent years in addressing the clinical and
pharmacological limitations of hydrogels for drug delivery applications but substantial …

The development of microgels/nanogels for drug delivery applications

JK Oh, R Drumright, DJ Siegwart… - Progress in polymer …, 2008 - Elsevier
Microgels/nanogels are crosslinked polymeric particles, which can be considered as
hydrogels if they are composed of water soluble/swellable polymer chains. They possess …

Polymeric gels and hydrogels for biomedical and pharmaceutical applications

J Jagur‐Grodzinski - Polymers for Advanced Technologies, 2010 - Wiley Online Library
Hydrogels are formed when a three‐dimensional polymeric network is loosely crosslinked.
They are swollen by water but not dissolved in it. Hydrogels may display reversible sol–gel …

Biodegradable and thermoreversible PCLA–PEG–PCLA hydrogel as a barrier for prevention of post-operative adhesion

Z Zhang, J Ni, L Chen, L Yu, J Xu, J Ding - Biomaterials, 2011 - Elsevier
Biodegradable polymers can serve as barriers to prevent the post-operative intestinal
adhesion. Herein, we synthesized a biodegradable triblock copolymer poly (ɛ-caprolactone …

Chitosan/TPP and chitosan/TPP-hyaluronic acid nanoparticles: systematic optimisation of the preparative process and preliminary biological evaluation

A Nasti, NM Zaki, P De Leonardis… - Pharmaceutical …, 2009 - Springer
Purpose Chitosan is one of the most sought-after components for designing nanoparticles
for drug delivery applications. However, despite the large number of studies, reproducibility …

Silk fibroin/polyacrylamide semi-interpenetrating network hydrogels for controlled drug release

BB Mandal, S Kapoor, SC Kundu - Biomaterials, 2009 - Elsevier
The present study describes a semi-interpenetrating network hydrogel fabricated using silk
fibroin/polyacrylamide for controlled drug delivery applications. Hydrogels were synthesized …

Highly elastomeric poly (glycerol sebacate)-co-poly (ethylene glycol) amphiphilic block copolymers

A Patel, AK Gaharwar, G Iviglia, H Zhang, S Mukundan… - Biomaterials, 2013 - Elsevier
Poly (glycerol sebacate)(PGS), a tough elastomer, has been proposed for tissue
engineering applications due to its desired mechanical properties, biocompatibility and …

Silk sericin/polyacrylamide in situ forming hydrogels for dermal reconstruction

B Kundu, SC Kundu - Biomaterials, 2012 - Elsevier
In situ forming tissue sealants are advantageous due to ease in application, complete
coverage of defect site and assured comfort levels to patients. The interconnected three …

Synthesis and characterization of pH-sensitive biodegradable polyurethane for potential drug delivery applications

L Zhou, L Yu, M Ding, J Li, H Tan, Z Wang… - Macromolecules, 2011 - ACS Publications
To obtain a pH-sensitive multifunctional polyurethane micelle drug carrier, a novel pH-
sensitive macrodiol containing acid-cleavable hydrazone linkers, poly (ε-caprolactone) …

Silk fibroin based interpenetrating network hydrogel for corneal stromal regeneration

P Bhattacharjee, M Ahearne - International Journal of Biological …, 2022 - Elsevier
There is a need to develop tissue engineering based approaches to address the shortage of
donor corneas worldwide for transplantation. To do this a novel approach to fabricate three …