Tuberculosis of the central nervous system in immunocompromised patients: HIV infection and solid organ transplant recipients

CA Nelson, JR Zunt - Clinical infectious diseases, 2011 - academic.oup.com
Central nervous system (CNS) tuberculosis (TB) is a devastating infection with high rates of
morbidity and mortality worldwide and may manifest as meningitis, tuberculoma, abscess, or …

Tuberculosis meningitis

K Bourgi, C Fiske, TR Sterling - Current infectious disease reports, 2017 - Springer
Abstract Purpose of Review As the most severe form of tuberculosis (TB), TB meningitis
disproportionately affects developing countries and results in significant morbidity and …

Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting

S Marais, DJ Pepper, C Schutz, RJ Wilkinson… - PloS one, 2011 - journals.plos.org
Background Mycobacterium tuberculosis is a common, devastating cause of meningitis in
HIV-infected persons. Due to international rollout programs, access to antiretroviral therapy …

Clinical Parameters, Routine Inflammatory Markers, and LTA4H Genotype as Predictors of Mortality Among 608 Patients With Tuberculous Meningitis in Indonesia

A van Laarhoven, S Dian, C Ruesen… - The Journal of …, 2017 - academic.oup.com
Background. Damaging inflammation is thought to contribute to the high morbidity and
mortality of tuberculous meningitis (TBM), but the link between inflammation and outcome …

Tuberculous meningitis in HIV-infected individuals

C Vinnard, RR Macgregor - Current HIV/AIDS Reports, 2009 - Springer
HIV-infected individuals are at increased risk for all forms of extrapulmonary tuberculosis,
including tuberculous meningitis. This risk is increased at more advanced levels of …

HIV-associated tuberculous meningitis–diagnostic and therapeutic challenges

S Marais, DJ Pepper, BJ Marais, ME Török - Tuberculosis, 2010 - Elsevier
HIV-associated tuberculous meningitis (TBM) poses significant diagnostic and therapeutic
challenges and carries a dismal prognosis. In this review, we present the clinical features …

Pretreatment cerebrospinal fluid bacterial load correlates with inflammatory response and predicts neurological events during tuberculous meningitis treatment

NTT Thuong, DN Vinh, HT Hai, DDA Thu… - The Journal of …, 2019 - academic.oup.com
Abstract Background The Mycobacterium tuberculosis load in the brain of individuals with
tuberculous meningitis (TBM) may reflect the host's ability to control the pathogen, determine …

Meningitis tuberculosa: claves para su diagnóstico y propuestas terapéuticas

M Lasso - Revista chilena de infectología, 2011 - SciELO Chile
El diagnóstico de la meningitis tuberculosa (MTBC) es siempre un desafío. Debemos dar
importancia a las manifestaciones clínicas y su duración. El análisis citoquímico del LCR …

Neurons are host cells for Mycobacterium tuberculosis

PJ Randall, NJ Hsu, D Lang, S Cooper… - Infection and …, 2014 - Am Soc Microbiol
Mycobacterium tuberculosis infection of the central nervous system is thought to be initiated
once the bacilli have breached the blood brain barrier and are phagocytosed, primarily by …

Clinical and radiological spectrum of intracranial tuberculosis: a hospital based study in Northeast India

B Synmon, M Das, AK Kayal, M Goswami… - Indian Journal of …, 2017 - Elsevier
Central nervous system tuberculosis (TB) is the most severe extra pulmonary TB having a
high mortality and morbidity. Objective To study the various clinical, biochemical, and …