Bio-based production of monomers and polymers by metabolically engineered microorganisms

H Chung, JE Yang, JY Ha, TU Chae, JH Shin… - Current opinion in …, 2015 - Elsevier
Highlights•Bio-based production of chemicals is becoming increasingly important.•Metabolic
engineering allows enhanced production of monomers and polymers.•Diamines …

Advances in the optimization of central carbon metabolism in metabolic engineering

Z Wu, X Liang, M Li, M Ma, Q Zheng, D Li, T An… - Microbial Cell …, 2023 - Springer
Central carbon metabolism (CCM), including glycolysis, tricarboxylic acid cycle and the
pentose phosphate pathway, is the most fundamental metabolic process in the activities of …

Metabolic engineering of Corynebacterium glutamicum for the production of 3-hydroxypropionic acid from glucose and xylose

Z Chen, J Huang, Y Wu, W Wu, Y Zhang, D Liu - Metabolic Engineering, 2017 - Elsevier
Hydroxypropionic acid (3-HP) is a promising platform chemical which can be used for the
production of various value-added chemicals. In this study, Corynebacterium glutamicum …

Current state and applications of microbial genome-scale metabolic models

WJ Kim, HU Kim, SY Lee - Current Opinion in Systems Biology, 2017 - Elsevier
Genome-scale metabolic models (GEMs) are valuable in describing an organism's entire
metabolism using genomic information and have made huge impact on systems biology and …

Toward glycerol biorefinery: metabolic engineering for the production of biofuels and chemicals from glycerol

Z Chen, D Liu - Biotechnology for biofuels, 2016 - Springer
As an inevitable by-product of the biofuel industry, glycerol is becoming an attractive
feedstock for biorefinery due to its abundance, low price and high degree of reduction …

Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …

Metabolic engineering of cyanobacteria for photosynthetic 3-hydroxypropionic acid production from CO2 using Synechococcus elongatus PCC 7942

EI Lan, DS Chuang, CR Shen, AM Lee, SY Ro… - Metabolic …, 2015 - Elsevier
Photosynthetic conversion of CO 2 to chemicals using cyanobacteria is an attractive
approach for direct recycling of CO 2 to useful products. 3-Hydroxypropionic acid (3HP) is a …

Metabolic engineering of Corynebacterium glutamicum for enhanced production of 5-aminovaleric acid

JH Shin, SH Park, YH Oh, JW Choi, MH Lee… - Microbial Cell …, 2016 - Springer
Abstract Background 5-Aminovaleric acid (5AVA) is an important five-carbon platform
chemical that can be used for the synthesis of polymers and other chemicals of industrial …

Recent advances in microbial production of fuels and chemicals using tools and strategies of systems metabolic engineering

C Cho, SY Choi, ZW Luo, SY Lee - Biotechnology advances, 2015 - Elsevier
The advent of various systems metabolic engineering tools and strategies has enabled more
sophisticated engineering of microorganisms for the production of industrially useful fuels …