Immunobiology of primary sclerosing cholangitis

M Cornillet, D Geanon, A Bergquist, NK Björkström - Hepatology, 2024 - journals.lww.com
Primary sclerosing cholangitis (PSC) is a chronic inflammatory progressive cholestatic liver
disease. Genetic risk factors, presence of autoantibodies, the strong clinical link with …

From immune dysregulation to organ dysfunction: understanding the enigma of Sepsis

Z Liu, Y Ting, M Li, Y Li, Y Tan, Y Long - Frontiers in Microbiology, 2024 - frontiersin.org
Sepsis is a syndrome precipitated by immune dysregulation in response to infection, and
represents a pivotal factor in global mortality attributed to diseases. The recent consensus …

Neutrophil percentage as a potential biomarker of acute kidney injury risk and short-term prognosis in patients with acute myocardial infarction in the elderly

Q Chen, Q Gu, A Yin, D Cai, T Xiao… - … Interventions in Aging, 2024 - Taylor & Francis
Objective This study aimed to explore the association of preoperative neutrophil percentage
(NEUT%) with the risk of acute kidney injury (AKI) in patients with acute myocardial infarction …

Neutrophil PPIF exacerbates lung ischemia–reperfusion injury after lung transplantation by promoting calcium overload-induced neutrophil extracellular traps …

W Wu, F Meng, H Zhang, H Tian, X Zhang - International …, 2024 - Elsevier
Lung ischemia–reperfusion (I/R) injury is the main risk factor for primary graft dysfunction
and patient death after lung transplantation (LTx). It is widely accepted that the main …

Suppression of overactivated immunity in the early stage is the key to improve the prognosis in severe burns

Y Xiang, B Pan, J Zhang, J Chen, H Fang… - Frontiers in …, 2024 - frontiersin.org
Background Severe burns can lead to systemic inflammatory response syndrome (SIRS)
and multiple organ dysfunction syndrome (MODS) due to inflammation-immunity …

[HTML][HTML] The Crucial Triad: Endothelial Glycocalyx, Oxidative Stress, and Inflammation in Cardiac Surgery—Exploring the Molecular Connections

B Ćurko-Cofek, M Jenko, G Taleska Stupica… - International journal of …, 2024 - mdpi.com
Since its introduction, the number of heart surgeries has risen continuously. It is a high-risk
procedure, usually involving cardiopulmonary bypass, which is associated with an …

The role of neutrophils in osteosarcoma: insights from laboratory to clinic

M Xia, Y Han, L Sun, D Li, C Zhu, D Li - Frontiers in Immunology, 2024 - frontiersin.org
Osteosarcoma, a highly aggressive malignant bone tumor, is significantly influenced by the
intricate interactions within its tumor microenvironment (TME), particularly involving …

Metabolism: a potential regulator of neutrophil fate

Z Yipeng, C Chao, L Ranran, P Tingting… - Frontiers in …, 2024 - frontiersin.org
Neutrophils are essential components of the innate immune system that defend against the
invading pathogens, such as bacteria, viruses, and fungi, as well as having regulatory roles …

[HTML][HTML] The Need for Standardized Guidelines for the Use of Monocyte Distribution Width (MDW) in the Early Diagnosis of Sepsis

A Piccioni, F Spagnuolo, S Baroni, G Savioli… - Journal of Personalized …, 2024 - mdpi.com
Sepsis is a complex and potentially life-threatening syndrome characterized by an abnormal
immune response to an infection, which can lead to organ dysfunction, septic shock, and …

Correlation between Peripheric Blood Markers and Surgical Invasiveness during Humeral Shaft Fracture Osteosynthesis in Young and Middle-Aged Patients

F Moldovan - Diagnostics, 2024 - mdpi.com
The treatment for humeral shaft fractures (HSFs) is still controversial, consisting of a wide
variety of orthopedic osteosynthesis materials that imply different grades of invasiveness …