The endoplasmic reticulum (ER) is an important organelle involved in protein quality control
and cellular homeostasis. The accumulation of unfolded proteins leads to an ER stress …

One evident hallmark of Alzheimer's disease (AD) is the irregular accumulation of proteins
due to changes in proteostasis involving endoplasmic reticulum (ER) stress. To alleviate ER …

Neuronal death and inflammatory response are two common pathological hallmarks of
acute central nervous system injury and chronic degenerative disorders, both of which are …

This narrative review summarises the evidence for considering physical exercise (PE) as a
non-pharmacological intervention for delaying cognitive decline in patients with Alzheimer's …

Multiple Sclerosis (MS) is a demyelinating disease of the human central nervous system
having an unconfirmed pathoetiology. Although animal models are used to mimic the …

Blast injuries include the various types of internal and external trauma caused by the impact
force of high-speed blast waves with multiple mechanisms involved. Thoracic blast exposure …

Background: The goal of slowing or halting the development of Alzheimer disease (AD) has
resulted in the huge allocation of resources by academic institutions and pharmaceutical …

Secretory and membrane proteins are folded in the endoplasmic reticulum (ER) prior to their
exit. When ER function is disturbed by exogenous and endogenous factors, such as heat …

Oligomeric forms of α-synuclein (α-syn) are critical in the formation of α-synuclein fibrils,
exhibiting neurotoxic properties that are pivotal in the pathogenesis of Parkinson's disease …

Abstract Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In addition to the pulmonary …