H Hu, FJ Xu - Biomaterials science, 2020 - pubs.rsc.org
Acute and chronic wounds cause severe physical trauma to patients and also bring an immense socio-economic burden. Hydrogels are considered to be effective wound …
T Zhu, J Mao, Y Cheng, H Liu, L Lv… - Advanced Materials …, 2019 - Wiley Online Library
Polysaccharide is an abundant and reproducible natural material that is biocompatible and biodegradable. Polysaccharide and its derivatives also possess distinctive properties such …
X Zhang, Y Li, Z Ma, D He, H Li - Bioactive materials, 2021 - Elsevier
More and more studies have recognized that the nanosized pores of hydrogels are too small for cells to normally grow and newly formed tissue to infiltrate, which impedes tissue …
EC Novosel, C Kleinhans, PJ Kluger - Advanced drug delivery reviews, 2011 - Elsevier
The main limitation in engineering in vitro tissues is the lack of a sufficient blood vessel system—the vascularization. In vivo almost all tissues are supplied by these endothelial cell …
P Wang, S Huang, Z Hu, W Yang, Y Lan, J Zhu… - Acta biomaterialia, 2019 - Elsevier
Excessive inflammation and reduced angiogenesis are two major obstacles in burn wound healing and skin regeneration. Here we report the fabrication and application of a …
A plethora of applications using polysaccharides have been developed in recent years due to their availability as well as their frequent nontoxicity and biodegradability. These polymers …
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and painless manner for patients has remained a central focus of next-generation diabetes …
Neovascularization is a critical determinant of wound-healing outcomes for deep burn injuries. We hypothesize that dextran-based hydrogels can serve as instructive scaffolds to …
MA Exley, L Hand, D O'Shea… - Journal of …, 2014 - joe.bioscientifica.com
Obesity is a major risk factor for metabolic disease, with white adipose tissue (WAT) inflammation emerging as a key underlying pathology. Alongside its major role in energy …