Therapeutics of Alzheimer's disease: Past, present and future

R Anand, KD Gill, AA Mahdi - Neuropharmacology, 2014 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

Pharmacology and pharmacokinetics of vitamin E: Nanoformulations to enhance bioavailability

AS Mohd Zaffarin, SF Ng, MH Ng… - International journal of …, 2020 - Taylor & Francis
Vitamin E belongs to the family of lipid-soluble vitamins and can be divided into two groups,
tocopherols and tocotrienols, with four isomers (alpha, beta, gamma and delta). Although …

[HTML][HTML] Antioxidant effects of vitamin E and risk of cardiovascular disease in women with obesity–A narrative review

AM Rychter, S Hryhorowicz, R Słomski, A Dobrowolska… - Clinical Nutrition, 2022 - Elsevier
Proper dietary habits are a vital element of cardiovascular (CV) treatment, and-according to
the current guidelines-a diet rich in antioxidants is generally recommended. It remains …

Antioxidant supplementation in oxidative stress-related diseases: What have we learned from studies on alpha-tocopherol?

FL Meulmeester, J Luo, LG Martens, K Mills… - Antioxidants, 2022 - mdpi.com
Oxidative stress has been proposed as a key contributor to lifestyle-and age-related
diseases. Because free radicals play an important role in various processes such as …

Vitamin E beyond its antioxidant label

A Ungurianu, A Zanfirescu, G Nițulescu, D Margină - Antioxidants, 2021 - mdpi.com
Vitamin E, comprising tocopherols and tocotrienols, is mainly known as an antioxidant. The
aim of this review is to summarize the molecular mechanisms and signaling pathways linked …

Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging

JE Slemmer, JJ Shacka, MI Sweeney… - Current medicinal …, 2008 - ingentaconnect.com
The overproduction of reactive oxygen species (ROS) and reactive nitrogen species (RNS)
is a common underlying mechanism of many neuropathologies, as they have been shown to …

An update on vitamin E, tocopherol and tocotrienol—perspectives

ML Colombo - Molecules, 2010 - mdpi.com
Vitamin E, like tocotrienols and tocopherols, is constituted of compounds essential for animal
cells. Vitamin E is exclusively synthesized by photosynthetic eukaryotes and other oxygenic …

Women with endometriosis improved their peripheral antioxidant markers after the application of a high antioxidant diet

J Mier-Cabrera, T Aburto-Soto… - Reproductive Biology …, 2009 - Springer
Background Oxidative stress has been identified in the peritoneal fluid and peripheral blood
of women with endometriosis. However, there is little information on the antioxidant intake …

Gene-regulatory activity of α-tocopherol

G Rimbach, J Moehring, P Huebbe, JK Lodge - Molecules, 2010 - mdpi.com
Vitamin E is an essential vitamin and a lipid soluble antioxidant, at least, under in vitro
conditions. The antioxidant properties of vitamin E are exerted through its phenolic hydroxyl …

Food antioxidant capacity determined by chemical methods may underestimate the physiological antioxidant capacity

J Serrano, I Goñi, F Saura-Calixto - Food Research International, 2007 - Elsevier
Antioxidant capacity assays are of growing interest in the study of dietary antioxidant
properties since they are able to analyse a complex mixture of antioxidants and its …