Background Mitochondrial dysfunction and metabolic reprogramming can lead to the
development and progression of hepatocellular carcinoma (HCC). Ferredoxin 1 (FDX1) is a …

Ferredoxins are proteins found in all biological kingdoms and are involved in essential
biological processes including photosynthesis, lipid metabolism, and biogeochemical …

Copper plays vital roles in numerous cellular processes and its imbalance can lead to
oxidative stress and dysfunction. Recent research has unveiled a unique form of copper …

The burden of cardiovascular disease (CVD) is rising in the Asia-Pacific region, in contrast to
falling CVD mortality rates in Europe and North America. To provide new insights into the …

Abstract Ferredoxin 1 and 2 (FDX1/2) constitute an evolutionarily conserved FDX family of
iron-sulfur cluster (ISC) containing proteins. FDX1/2 are cognate substrates of ferredoxin …

As women age, oocytes are susceptible to a myriad of dysfunctions, including mitochondrial
dysfunction, impaired DNA repair mechanisms, epigenetic alterations, and metabolic …

Objective To investigate the effects of disulfiram (DSF) combined with Cu2+ on the
proliferation, migration and invasion of hepatoma Hep3B cells and the underlying …

Atherosclerotic coronary artery disease (CAD), the leading cause of mortality worldwide, is
influenced by both genetic and environmental factors. Despite the identification of over 250 …