Blood pressure regulation IX: cerebral autoregulation under blood pressure challenges

YC Tzeng, PN Ainslie - European journal of applied physiology, 2014 - Springer
Cerebral autoregulation (CA) is integral to the delicate process of maintaining stable
cerebral perfusion and brain tissue oxygenation against changes in arterial blood pressure …

Are we ready for clinical therapy based on cerebral autoregulation? A pro-con debate

A Sarwal, C Robba, C Venegas, W Ziai, M Czosnyka… - Neurocritical care, 2023 - Springer
Cerebral autoregulation (CA) is a physiological mechanism that maintains constant cerebral
blood flow regardless of changes in cerebral perfusion pressure and prevents brain damage …

The frequency response of cerebral autoregulation

CD Fraser III, KM Brady, CJ Rhee… - Journal of Applied …, 2013 - journals.physiology.org
The frequency-response of pressure autoregulation is not well delineated; therefore, the
optimal frequency of arterial blood pressure (ABP) modulation for measuring autoregulation …

Differential hemodynamic response of pial arterioles contributes to a quadriphasic cerebral autoregulation physiology

SP Klein, V De Sloovere, G Meyfroidt… - Journal of the …, 2022 - Am Heart Assoc
Background Cerebrovascular autoregulation (CA) regulates cerebral vascular tone to
maintain near‐constant cerebral blood flow during fluctuations in cerebral perfusion …

An optimal frequency range for assessing the pressure reactivity index in patients with traumatic brain injury

T Howells, U Johnson, T McKelvey… - Journal of clinical …, 2015 - Springer
The objective of this study was to identify the optimal frequency range for computing the
pressure reactivity index (PRx). PRx is a clinical method for assessing cerebral pressure …

Continuous time-domain cerebrovascular reactivity metrics and discriminate capacity for the upper and lower limits of autoregulation: a scoping review of the animal …

AS Sainbhi, L Froese, A Gomez, C Batson… - Neurotrauma …, 2021 - liebertpub.com
Over a wide range of systemic arterial pressures, cerebral blood flow (CBF) is regulated
fairly constantly by the cerebral vessels in a process termed cerebral autoregulation (CA) …

Cerebrovascular pressure reactivity in children with traumatic brain injury

PM Lewis, M Czosnyka, BG Carter… - Pediatric Critical Care …, 2015 - journals.lww.com
Objective: Traumatic brain injury is a significant cause of morbidity and mortality in children.
Cerebral autoregulation disturbance after traumatic brain injury is associated with worse …

Dynamic cerebral autoregulation in acute intracerebral hemorrhage

M Oeinck, F Neunhoeffer, KJ Buttler, S Meckel… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Cerebral autoregulation (CA) is not universally impaired in acute
intracerebral hemorrhage (ICH); however, the dynamic components of CA are probably …

Cerebral blood flow autoregulation in sepsis for the intensivist: why its monitoring may be the future of individualized care

CM Goodson, K Rosenblatt… - Journal of intensive …, 2018 - journals.sagepub.com
Cerebral blood flow (CBF) autoregulation maintains consistent blood flow across a range of
blood pressures (BPs). Sepsis is a common cause of systemic hypotension and cerebral …

Continuous monitoring of the lower limit of reactivity in traumatic brain injury patients: understanding what is feasible

E Beqiri, J Donnelly, M Aries, A Ercole, P Smielewski - Critical Care, 2023 - Springer
A few months ago, we published our work 'The Lower Limit of Reactivity as a potential
individualised Cerebral Perfusion Pressure target in Traumatic Brain Injury: a CENTER-TBI …