More than any other cytokine family, the 11 members of the IL-1 family are associated with
innate immune responses, which occur in acute inflammation and chronic inflammatory …

Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology
usually affecting young adults; spiking fever, arthritis and evanescent rash are commonly …

Abstract Background Adult-onset Still's disease (AOSD) is a rare systemic inflammatory
disorder of unknown etiology, characterized by a clinical triad of high spiking fever …

Adult-onset Still's disease (AoSD) is a rare but clinically well-known, polygenic, systemic
autoinflammatory disease. Owing to its sporadic appearance in all adult age groups with …

Interleukin-1 (IL-1) is the prototypical inflammatory cytokine: two distinct ligands (IL-1α and IL-
1β) bind the IL-1 type 1 receptor (IL-1R1) and induce a myriad of secondary inflammatory …

Objectives Adult-onset Still's disease (AOSD) is a rare systemic autoinflammatory disease;
its management is largely empirical. This is the first clinical study to determine if interleukin …

Systemic juvenile idiopathic arthritis and adult-onset Still's disease are rare
autoinflammatory disorders with common features, supporting the recognition of these being …

Adult-onset Still's disease (AoSD) is a rare systemic autoinflammatory disease characterized
by arthritis, spiking fever, skin rash and elevated ferritin levels. The reason behind the …

Adult-onset Still's disease (AOSD) is a rare disease affecting multiple systems and organs
with unknown etiology, and the clinical symptoms are usually described as spiking fever …

We performed a comprehensive systematic targeted literature review and used the Delphi
method to formulate expert consensus statements to guide the treatment of adult-onset Still's …