Endothelial function in cardiovascular medicine: a consensus paper of the European society of cardiology working groups on atherosclerosis and vascular biology …

Y Alexander, E Osto, A Schmidt-Trucksäss… - Cardiovascular …, 2021 - academic.oup.com
Endothelial cells (ECs) are sentinels of cardiovascular health. Their function is reduced by
the presence of cardiovascular risk factors, and is regained once pathological stimuli are …

Extracellular vesicles in cardiovascular disease: potential applications in diagnosis, prognosis, and epidemiology

F Jansen, G Nickenig, N Werner - Circulation research, 2017 - Am Heart Assoc
Extracellular vesicles originate from diverse subcellular compartments and are released in
the extracellular space. By transferring their cargoes into target cells and tissues, they now …

Biology and role of extracellular vesicles (EVs) in the pathogenesis of thrombosis

M Zarà, GF Guidetti, M Camera, I Canobbio… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs) are well-established mediators of cell-to-cell communication.
EVs can be released by every cell type and they can be classified into three major groups …

The role of circulating biomarkers in peripheral arterial disease

G Saenz-Pipaon, E Martinez-Aguilar, J Orbe… - International Journal of …, 2021 - mdpi.com
Peripheral arterial disease (PAD) of the lower extremities is a chronic illness predominantly
of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is …

Vascular calcification and cellular signaling pathways as potential therapeutic targets

JH Kang, T Kawano, M Murata, R Toita - Life Sciences, 2024 - Elsevier
Increased vascular calcification (VC) is observed in patients with cardiovascular diseases
such as atherosclerosis, diabetes, and chronic kidney disease. VC is divided into three types …

circRNA‑0006896‑miR1264‑DNMT1 axis plays an important role in carotid plaque destabilization by regulating the behavior of endothelial cells in atherosclerosis

Y Wen, Y Chun, ZQ Lian, ZW Yong… - Molecular …, 2021 - spandidos-publications.com
Atherosclerosis (AS) is a chronic inflammatory disease of the vascular wall with multiple
causes. AS is the primary pathological basis of cardiovascular disease and stroke …

[HTML][HTML] Review of serum biomarkers in carotid atherosclerosis

E Martinez, J Martorell, V Riambau - Journal of Vascular Surgery, 2020 - Elsevier
Background Carotid artery atherosclerotic stenosis is a preventable major cause of stroke,
but there is still a need for definition of high-risk plaque in asymptomatic patients who might …

Could SCGF-beta levels be associated with inflammation markers and insulin resistance in male patients suffering from obesity-related NAFLD?

G Tarantino, V Citro, C Balsano, D Capone - Diagnostics, 2020 - mdpi.com
One of the pathologic hallmarks of obesity is macrophage infiltration of adipose tissue that
has been confirmed as source of multipotent adult stem cells. Stem cell growth factor-beta …

Targeting QKI-7 in vivo restores endothelial cell function in diabetes

C Yang, M Eleftheriadou, S Kelaini, T Morrison… - Nature …, 2020 - nature.com
Vascular endothelial cell (EC) dysfunction plays a key role in diabetic complications. This
study discovers significant upregulation of Quaking-7 (QKI-7) in iPS cell-derived ECs when …

Role of extracellular vesicles as potential diagnostic and/or therapeutic biomarkers in chronic cardiovascular diseases

JL Martin-Ventura, C Roncal, J Orbe… - Frontiers in cell and …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are the first cause of death worldwide. In recent years,
there has been great interest in the analysis of extracellular vesicles (EVs), including …