Clinical use of molecular data in thyroid nodules and cancer

AS Alzahrani - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Over the past 3 decades, advances in the molecular genetics of thyroid cancer (TC) have
been translated into diagnostic tests, prognostic markers, and therapeutic agents. The main …

The relationship between thyrotropin serum concentrations and thyroid carcinoma

X Zhang, L Tian, D Teng, W Teng - Cancers, 2023 - mdpi.com
Simple Summary Thyroid-stimulating hormone (TSH) plays a role in the regulation of thyroid
hormones and is an important indicator for assessing thyroid function. Thyroid cancer (TC) is …

Could oxidative stress play a role in the development and clinical management of differentiated thyroid cancer?

M Kościuszko, A Buczyńska, AJ Krętowski… - Cancers, 2023 - mdpi.com
Simple Summary Increased oxidative stress (OS) has been implicated as a relevant risk
factor for cancer development and progression. The incidence of differentiated thyroid …

Management of radioiodine refractory differentiated thyroid cancer: the Latin American perspective

F Pitoia, RS Scheffel, I Califano, A Gauna… - Reviews in Endocrine …, 2024 - Springer
Radioiodine (RAI) refractory differentiated thyroid cancer is an uncommon and challenging
situation that requires a multidisciplinary approach to therapeutic strategies. The definition of …

Iodine nutrition and papillary thyroid cancer

X Zhang, F Zhang, Q Li, C Feng, W Teng - Frontiers in Nutrition, 2022 - frontiersin.org
Thyroid cancer (TC) is the most frequent endocrine malignancy. The incidence of TC,
especially papillary thyroid carcinoma (PTC), has continued to rise all over the world during …

Autoimmune thyroid disease and differentiated thyroid carcinoma: A review of the mechanisms that explain an intriguing and exciting relationship

H Vargas-Uricoechea - World Journal of Oncology, 2023 - pmc.ncbi.nlm.nih.gov
Autoimmune thyroid disease is a complex and highly frequent disease, where a wide variety
of genetic, epigenetic and environmental factors (among others) come together and interact …

High aggressiveness of papillary thyroid cancer: from clinical evidence to regulatory cellular networks

J Zhang, S Xu - Cell Death Discovery, 2024 - nature.com
The global incidence of thyroid cancer has increased over recent decades. Papillary thyroid
cancer (PTC) is the most common type of thyroid cancer and accounts for nearly 90% of all …

Molecular testing for thyroid nodules: Where are we now?

C Ferraz - Reviews in Endocrine and Metabolic Disorders, 2024 - Springer
Approximately 25% of the fine needle aspiration samples (FNAB) of thyroid nodules are
classified as “indeterminate samples”, that means, Bethesda III and IV categories. Until the …

Immune microenvironment in papillary thyroid carcinoma: roles of immune cells and checkpoints in disease progression and therapeutic implications

X Zheng, R Sun, T Wei - Frontiers in Immunology, 2024 - frontiersin.org
Papillary thyroid cancer (PTC) is the most common type of primary thyroid cancer. Despite
the low malignancy and relatively good prognosis, some PTC cases are highly aggressive …

Circular RNAs: Characteristics, functions, mechanisms, and potential applications in thyroid cancer

M Wu, H Yuan, W Zou, S Xu, S Liu, Q Gao… - Clinical and …, 2024 - Springer
Thyroid cancer (TC) is one of the most common endocrine malignancies, and its incidence
has increased globally. Despite extensive research, the underlying molecular mechanisms …