[HTML][HTML] Normal and glaucomatous outflow regulation

TS Acott, JA Vranka, KE Keller, VK Raghunathan… - Progress in retinal and …, 2021 - Elsevier
Glaucoma remains only partially understood, particularly at the level of intraocular pressure
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …

The vital role for nitric oxide in intraocular pressure homeostasis

E Reina-Torres, ML De Ieso, LR Pasquale… - Progress in retinal and …, 2021 - Elsevier
Catalyzed by endothelial nitric oxide (NO) synthase (eNOS) activity, NO is a gaseous
signaling molecule maintaining endothelial and cardiovascular homeostasis. Principally, NO …

An emerging treatment option for glaucoma: Rho kinase inhibitors

SK Wang, RT Chang - Clinical ophthalmology, 2014 - Taylor & Francis
Rho kinase (ROCK) inhibitors are a novel potential class of glaucoma therapeutics with
multiple compounds currently in Phase II and III US Food and Drug Administration trials in …

Aqueous angiographic outflow improvement after trabecular microbypass in glaucoma patients

AS Huang, RC Penteado, V Papoyan… - Ophthalmology …, 2019 - Elsevier
Purpose To study changes in aqueous humor outflow (AHO) patterns after trabecular
microbypass (TMB) in glaucoma patients using intraoperative sequential aqueous …

Fluorescein aqueous angiography in live normal human eyes

AS Huang, RC Penteado, SK Saha, JL Do… - Journal of …, 2018 - journals.lww.com
Purpose: To evaluate aqueous humor outflow (AHO) in intact eyes of live human subjects
during cataract surgery using fluorescein aqueous angiography. Methods: Aqueous …

[HTML][HTML] Aqueous outflow regulation–21st century concepts

M Johnstone, C Xin, J Tan, E Martin, J Wen… - Progress in retinal and …, 2021 - Elsevier
We propose an integrated model of aqueous outflow control that employs a pump-conduit
system in this article. Our model exploits accepted physiologic regulatory mechanisms such …

Iridocorneal angle imaging of a human donor eye by spectral-domain optical coherence tomography

S Luo, G Holland, R Khazaeinezhad, S Bradford… - Scientific Reports, 2023 - nature.com
Iridocorneal angle (ICA) details particularly the trabecular meshwork (TM), Schlemm's canal
(SC), and collector channels (CCs) play crucial roles in the regulation of the aqueous …

Aqueous angiography in living nonhuman primates shows segmental, pulsatile, and dynamic angiographic aqueous humor outflow

AS Huang, M Li, D Yang, H Wang, N Wang… - Ophthalmology, 2017 - Elsevier
Purpose To evaluate the feasibility of safely performing aqueous angiography in intact eyes
of living nonhuman primates (NHPs) for evaluating aqueous humor outflow and segmental …

Comparison of pulse wave signal monitoring techniques with different fiber-optic interferometric sensing elements

N Ushakov, A Markvart, D Kulik, L Liokumovich - Photonics, 2021 - mdpi.com
Pulse wave (PW) measurement is a highly prominent technique, used in biomedical
diagnostics. Development of novel PW sensors with increased accuracy and reduced …

Morphological and biomechanical analyses of the human healthy and glaucomatous aqueous outflow pathway: imaging-to-modeling

A Karimi, DJ Crouch, R Razaghi, JC Downs… - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective: Intraocular pressure (IOP) is maintained via a dynamic
balance between the production of aqueous humor and its drainage through the trabecular …