Non-coding RNAs and glioma: Focus on cancer stem cells

A Rajabi, M Kayedi, S Rahimi, F Dashti… - Molecular Therapy …, 2022 - cell.com
Glioblastoma and gliomas can have a wide range of histopathologic subtypes. These
heterogeneous histologic phenotypes originate from tumor cells with the distinct functions of …

Mechanisms of long non-coding RNAs in biological characteristics and aerobic glycolysis of glioma

N Zhao, J Zhang, Q Zhao, C Chen, H Wang - International Journal of …, 2021 - mdpi.com
Glioma is the most common and aggressive tumor of the central nervous system. The
uncontrolled proliferation, cellular heterogeneity, and diffusive capacity of glioma cells …

The involvement of long non-coding RNAs in glioma: from early detection to immunotherapy

X Wu, L Yang, J Wang, Y Hao, C Wang… - Frontiers in …, 2022 - frontiersin.org
Glioma is a brain tumor that arises in the central nervous system and is categorized
according to histology and molecular genetic characteristics. Long non-coding RNAs …

[HTML][HTML] Association of glioma CD44 expression with glial dynamics in the tumour microenvironment and patient prognosis

Z Du, Y Wang, J Liang, S Gao, X Cai, Y Yu, Z Qi… - Computational and …, 2022 - Elsevier
Because of the heterogeneity of lower-grade gliomas (LGGs), patients show various survival
outcomes that are not reliably predicted by histological classification. The tumour …

Downregulation of enhancer RNA AC003092. 1 is associated with poor prognosis in kidney renal clear cell carcinoma

JJ Li, JZ Gan, C Chen, Y Yuan, X Xiong, L Li, P Luo… - Scientific Reports, 2024 - nature.com
Kidney renal clear cell carcinoma (KIRC) is the most common histological type of renal
cancer, enhancer RNA plays a significant role in tumor growth, however, it has been less …

Insights into enhancer RNAs: biogenesis and emerging role in brain diseases

Y Shen, Z Huang, R Yang, Y Chen… - The …, 2023 - journals.sagepub.com
Enhancers are cis-acting elements that control the transcription of target genes and are
transcribed into a class of noncoding RNAs (ncRNAs) termed enhancer RNAs (eRNAs) …

Tobacco smoke and electronic cigarette vapor alter enhancer rna expression that can regulate the pathogenesis of lung squamous cell carcinoma

JC Tsai, OA Saad, S Magesh, J Xu, AC Lee, WT Li… - Cancers, 2021 - mdpi.com
Simple Summary It is well established that tobacco smoke is the key player in lung
squamous cell carcinoma (LUSC) pathogenesis, and there is growing evidence that …

Current advances on the important roles of enhancer RNAs in molecular pathways of cancer

R Wang, Q Tang - International Journal of Molecular Sciences, 2021 - mdpi.com
Enhancers are critical genomic elements that can cooperate with promoters to regulate gene
transcription in both normal and cancer cells. Recent studies reveal that enhancer regions …

[HTML][HTML] Identification of an immune-related eRNA prognostic signature for clear cell renal cell carcinoma

Y Lv, L Niu, Q Li, W Shao, X Yan, Y Li, Y Yue… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Immune-related enhancer RNAs (eRNAs) have garnered significant attention
in cancer metabolism research, yet their specific roles in ccRCC have remained elusive …

Inflammatory immune-associated eRNA: mechanisms, functions and therapeutic prospects

L Wan, W Li, Y Meng, Y Hou, M Chen, B Xu - Frontiers in Immunology, 2022 - frontiersin.org
The rapid development of multiple high-throughput sequencing technologies has made it
possible to explore the critical roles and mechanisms of functional enhancers and enhancer …