Traditional organic synthesis relies heavily on organic solvents for a multitude of tasks,
including dissolving the components and facilitating chemical reactions, because many …

The cooperation and interplay between organic and metal catalyst systems is of utmost
importance in nature and chemical synthesis. Here innovative and selective cooperative …

Recent developments in catalytic asymmetric aldol reactions have been summarized.
Enantioselective aldol reactions are important methods to synthesize β-hydroxy carbonyl …

Organic syntheses are composed of two main types of reactions: Carbon-carbon bond
formations and functional group transformations. CC bond formation is the essence of …

Asymmetric aldol reactions are a powerful method for the construction of carbon–carbon
bonds in an enantioselective fashion. Historically this reaction has been performed in a …

Significance: Siloxyproline catalysts have been identified as effective catalysts for the
enantioselective direct aldol reaction in water without using an organic solvent. With 10 …

Abstract (Figure Presented) What expression best conveys the recent examples of"
aqueous" organocatalyzed aldol reactions? It is suggested that a reaction occurs" in water" if …

In nature there are at least nineteen different acyclic amino acids that act as the building
blocks of polypeptides and proteins with different functions. Here we report that α‐amino …

l-Proline moieties bound to a thermoresponsive polymer nanoreactor efficiently directed the
asymmetric aldol reaction in water with excellent yields and enantioselectivity (ee). The …

Aldol reactions have been and are widely applied for the preparation of β-hydroxy
aldehydes, β-hydroxy ketones or α, β-unsaturated aldehydes or ketones through addition or …