[HTML][HTML] Porous scaffolds for bone regeneration

N Abbasi, S Hamlet, RM Love, NT Nguyen - Journal of science: advanced …, 2020 - Elsevier
Globally, bone fractures due to osteoporosis occur every 20 s in people aged over 50 years.
The significant healthcare costs required to manage this problem are further exacerbated by …

How does scaffold porosity conduct bone tissue regeneration?

H Mohammadi, M Sepantafar… - Advanced …, 2021 - Wiley Online Library
Pores play a crucial role in bone regeneration as they allow the exchange of nutrition and
oxygen, expulsion of waste products, and bone tissue and vascular ingrowth through the …

[HTML][HTML] Stem cell therapies in tendon-bone healing

Y Xu, WX Zhang, LN Wang, YQ Ming… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Tendon-bone insertion injuries such as rotator cuff and anterior cruciate ligament injuries
are currently highly common and severe. The key method of treating this kind of injury is the …

[HTML][HTML] Microenvironment responsive hypoxia-mimetic DFO composite hydrogel for on-demand neovascularization to promote tendon-to-bone healing

C Xu, T Lin, X Zhao, Y Gan, J Huang, J Zhang… - Composites Part B …, 2023 - Elsevier
Due to the particularity of the tendon-to-bone interface, the integration of tendon graft and
bone after anterior cruciate ligament (ACL) reconstruction is the key to the success of the …

Tackling the challenges of graft healing after anterior cruciate ligament reconstruction—thinking from the endpoint

S Yao, PSH Yung, PPY Lui - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Anterior cruciate ligament (ACL) tear is common in sports and accidents, and accounts for
over 50% of all knee injuries. ACL reconstruction (ACLR) is commonly indicated to restore …

Biomaterials developed for facilitating healing outcome after anterior cruciate ligament reconstruction: efficacy, surgical protocols, and assessments using preclinical …

X He, Y Li, J Guo, J Xu, H Zu, L Huang, MT Ong… - Biomaterials, 2021 - Elsevier
Anterior cruciate ligament (ACL) reconstruction is the recommended treatment for ACL tear
in the American Academy of Orthopaedic Surgeons (AAOS) guideline. However, not a small …

Bioactive tape with BMP-2 binding peptides captures endogenous growth factors and accelerates healing after anterior cruciate ligament reconstruction

JF Crispim, SC Fu, YW Lee… - … American journal of …, 2018 - journals.sagepub.com
Background: The anterior cruciate ligament (ACL) has poor regenerative capacity, and an
injury leads to loss of function, limiting quality of life and increasing the incidence of …

Slit guidance ligand 3 (SLIT3) loaded in hydrogel microparticles enhances the tendon-bone healing through promotion of type-H vessel formation: an experimental …

J Li, G Wu, C Xu, Z Cai, J Ji, Z Yu, J Zhang… - International Journal of …, 2023 - mdpi.com
Poor tendon–bone interface (TBI) integration is one of the major causes contributing to
unsatisfactory healing quality in patients after anterior cruciate ligament (ACL) …

Fabrication and characterization of electroconductive/osteoconductive hydrogel nanocomposite based on poly (dopamine-co-aniline) containing calcium phosphate …

S Paknia, Z Izadi, M Moosaipour, S Moradi… - Journal of Molecular …, 2022 - Elsevier
This study aimed to integrate the unique benefits of electroconductive hydrogel scaffold and
hydroxyapatite (HAp) crystals in the repair of bone defects. For this objective, HAp crystals …

Application of stem cell therapy for ACL graft regeneration

C Wang, Y Hu, S Zhang, D Ruan, Z Huang… - Stem cells …, 2021 - Wiley Online Library
Graft regeneration after anterior cruciate ligament (ACL) reconstruction surgery is a complex
three‐stage process, which usually takes a long duration and often results in fibrous scar …