Mechanisms of cadmium-induced testicular injury: a risk to male fertility

W Ali, Y Ma, J Zhu, H Zou, Z Liu - Cells, 2022 - mdpi.com
Cadmium is a heavy toxic metal with unknown biological functions in the human body. Over
time, cadmium accretion in the different visceral organs (liver, lungs, kidney, and testis) is …

Influence of iron on bone homeostasis

E Balogh, G Paragh, V Jeney - Pharmaceuticals, 2018 - mdpi.com
Bone homeostasis is a complex process, wherein osteoclasts resorb bone and osteoblasts
produce new bone tissue. For the maintenance of skeletal integrity, this sequence has to be …

Moderate to severe liver siderosis and raised AST are independent risk factors for vitamin D insufficiency in β-thalassemia patients

H Darvishi-Khezri, H Karami, M Naderisorki… - Scientific Reports, 2020 - nature.com
Numerous problematic disorders such as vitamin D (Vit-D) deficiency subsequent to large
iron loading can be developed in patients with β-thalassemia. The study aimed to estimate …

Endocrinopathies in Hemoglobinopathies: What Is the Role of Iron?

P Evangelidis, TM Venou, B Fani, E Vlachaki… - International Journal of …, 2023 - mdpi.com
Hemoglobinopathies, including β-thalassemia and sickle cell disease (SCD), are common
genetic blood disorders. Endocrine disorders are frequent manifestations of organ damage …

New entity—thalassemic endocrine disease: major beta-thalassemia and endocrine involvement

M Carsote, C Vasiliu, AI Trandafir, SE Albu… - Diagnostics, 2022 - mdpi.com
Beta-thalassemia (BTH), a recessively inherited haemoglobin (Hb) disorder, causes iron
overload (IO), extra-medullary haematopoiesis and bone marrow expansion with major …

Association between osteoporosis and low hemoglobin levels: a nested case–control study using a national health screening cohort

SY Kim, DM Yoo, C Min, HG Choi - International Journal of Environmental …, 2021 - mdpi.com
An association between anemia and an increased risk of osteoporosis has been suggested.
The goal of this study was to estimate the association of hemoglobin (Hb) level with …

Hematological diseases and osteoporosis

A Gaudio, A Xourafa, R Rapisarda, L Zanoli… - International Journal of …, 2020 - mdpi.com
Secondary osteoporosis is a common clinical problem faced by bone specialists, with a
higher frequency in men than in women. One of several causes of secondary osteoporosis is …

Endocrinopathies in beta thalassemia: a narrative review

TM Venou, F Barmpageorgopoulou, M Peppa… - Hormones, 2024 - Springer
Beta thalassemia is the most common genetic blood disorder, characterized by reduced
production or complete absence of beta-globin chains. The combination of systematic red …

Efficacy and safety of teriparatide in beta-thalassemia major associated osteoporosis: a real-life experience

I Gagliardi, M Celico, MR Gamberini, M Pontrelli… - Calcified Tissue …, 2022 - Springer
Osteoporosis represents a relevant cause of morbidity in adult Thalassemia Major (TM)
population. Antiresorptive drugs such as bisphosphonates were demonstrated effective in …

Vitamin D, bone metabolism, and fracture risk in polycystic ovary syndrome

F Di Bari, A Catalano, F Bellone, G Martino… - Metabolites, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among
premenopausal women. PCOS may have reproductive, metabolic, cardiovascular, and …