Sarcoma care in the era of precision medicine
K Wallander, I Öfverholm, K Boye… - Journal of Internal …, 2023 - Wiley Online Library
Sarcoma subtype classification is currently mainly based upon histopathological
morphology. Molecular analyses have emerged as an efficient addition to the diagnostic …
morphology. Molecular analyses have emerged as an efficient addition to the diagnostic …
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial
INTRIGUE was an open-label, phase 3 study in adult patients with advanced gastrointestinal
stromal tumor who had disease progression on or intolerance to imatinib and who were …
stromal tumor who had disease progression on or intolerance to imatinib and who were …
Molecular Advances in the Treatment of Advanced Gastrointestinal Stromal Tumor
V Venkataraman, S George, GM Cote - The Oncologist, 2023 - academic.oup.com
Most gastrointestinal stromal tumors (GIST) are driven by activating mutations in Proto-
oncogene c-KIT (KIT) or PDGFRA receptor tyrosine kinases (RTK). The emergence of …
oncogene c-KIT (KIT) or PDGFRA receptor tyrosine kinases (RTK). The emergence of …
[HTML][HTML] Improving the Prognostic and Predictive Value of Circulating Tumor Cell Enumeration: Is Longitudinal Monitoring the Answer?
A Fabisiewicz, M Szostakowska-Rodzos… - International Journal of …, 2024 - mdpi.com
Circulating tumor cell (CTC) numbers in the blood of cancer patients can indicate the
progression and invasiveness of tumors, and their prognostic and predictive value has been …
progression and invasiveness of tumors, and their prognostic and predictive value has been …
Emerging targeted therapeutic strategies to overcome imatinib resistance of gastrointestinal stromal tumors
MT Masucci, ML Motti, M Minopoli… - International Journal of …, 2023 - mdpi.com
Gastrointestinal stromal tumors (GISTs) are the most common malignant mesenchymal
neoplasms of the gastrointestinal tract. The gold standard for the diagnosis of GISTs is …
neoplasms of the gastrointestinal tract. The gold standard for the diagnosis of GISTs is …
[HTML][HTML] Angiogenesis in gastrointestinal stromal tumors: From bench to bedside
Gastrointestinal stromal tumors (GISTs) are rare neoplasms with an estimated incidence
from 0.78 to 1-1.5 patients per 100000. They most commonly occur in the elderly during the …
from 0.78 to 1-1.5 patients per 100000. They most commonly occur in the elderly during the …
Analytical validation of a novel comprehensive genomic profiling informed circulating tumor DNA monitoring assay for solid tumors
DR Zollinger, E Rivers, A Fine, Y Huang, J Son… - Plos one, 2024 - journals.plos.org
Emerging technologies focused on the detection and quantification of circulating tumor DNA
(ctDNA) in blood show extensive potential for managing patient treatment decisions …
(ctDNA) in blood show extensive potential for managing patient treatment decisions …
Monitoring advanced gastrointestinal stromal tumor with circulating tumor DNA
D Gómez-Peregrina, CM Cicala… - Current Opinion in …, 2024 - journals.lww.com
The dynamic field of ctDNA technologies is rapidly evolving and holds significant promise for
research. Several trials have successfully validated the clinical utility of ctDNA in metastatic …
research. Several trials have successfully validated the clinical utility of ctDNA in metastatic …
[HTML][HTML] 循环肿瘤DNA 检测在胃肠间质瘤诊疗中的价值
王盛锦， 王峰， 孙锋 - 南京医科大学学报(自然科学版), 2023 - jnmu.njmu.edu.cn
摘要胃肠间质瘤(gastrointestinal stromal tumor, GIST) 起源于胃肠道间叶组织, 多数继发于KIT
及血小板源性生长因子受体α (platelet derived growth factor receptor alpha, PDGFRA) …
及血小板源性生长因子受体α (platelet derived growth factor receptor alpha, PDGFRA) …
Analytic validation of an FGFR-focused cell-free DNA liquid biopsy assay (FGFR-Dx)
JW Reeser, MR Wing, E Samorodnitsky, T Dao… - medRxiv, 2024 - medrxiv.org
Commercial liquid biopsy assays are routinely used by oncologists to monitor disease
response and resistance to therapy. Additionally, in cases where tumor tissue is not …
response and resistance to therapy. Additionally, in cases where tumor tissue is not …