Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

All cells sense and integrate mechanical and biochemical cues from their environment to
orchestrate organismal development and maintain tissue homeostasis …

Oligodendrocyte precursor cells (OPCs) originate in localized germinal zones in the
embryonic neural tube, then migrate and proliferate to populate the entire central nervous …

Neurogenesis persists in selected regions of the adult mouse brain; among them, the
ventricular-subventricular zone (V-SVZ) of the lateral ventricles represents a major …

The extracellular matrix (ECM) is a dynamic and complex network of proteins and molecules
that surrounds cells and tissues in the nervous system and orchestrates a myriad of …

Dystroglycan is a cell membrane protein that binds to the extracellular matrix in a variety of
mammalian tissues. The α-subunit of dystroglycan (αDG) is heavily glycosylated, including a …

Osteochondral damage from trauma or osteoarthritis is a general joint disease that can lead
to an increased social and economic burden in the modern society. The inefficiency of …

Multiciliated cells of the airways, brain ventricles, and female reproductive tract provide the
motive force for mucociliary clearance, cerebrospinal fluid circulation, and ovum transport …

Axon guidance requires interactions between extracellular signaling molecules and
transmembrane receptors, but how appropriate context-dependent decisions are …

Dystroglycan (DG) is a glycoprotein composed of two subunits that remain non-covalently
bound at the plasma membrane: α-DG, which is extracellular and heavily O-mannosyl …