Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of
natural killer (NK) cells, some NKT cells, CD8+ cytotoxic T cells, γδ T cells, and under certain …

Infections with human cytomegalovirus (HCMV) are a major cause of morbidity and mortality
in humans with acquired or developmental deficits in innate and adaptive immunity. In the …

The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …

NKG2D (natural-killer group 2, member D) is a powerful activating receptor expressed by
natural killer (NK) cells and T cells that regulates immune responses during infection, cancer …

Tissue-resident memory T cells (T RM) reside in barrier tissues and provide local immediate
protective immunity. Here, we show that the salivary gland (SG) most-effectively induces …

Effective immunity requires the coordinated activation of innate and adaptive immune
responses. Natural killer (NK) cells are central innate immune effectors, but can also affect …

Dendritic cells (DCs) regulate various aspects of innate immunity, including natural killer
(NK) cell function. Here we define the mechanisms involved in DC–NK cell interactions …

Human cytomegalovirus (HCMV) employs a variety of strategies to modify or evade the host
immune response, and natural killer (NK) cells play a crucial role in controlling …

Human and mouse NKG 2D ligands (NKG 2 DL s) are absent or only poorly expressed by
most normal cells but are upregulated by cell stress, hence, alerting the immune system in …

Human cytomegalovirus (HCMV) has become a paradigm for viral immune evasion due to
its unique multitude of immune-modulatory strategies. HCMV modulates the innate as well …