A fresh look at zebrafish from the perspective of cancer research

S Zhao, J Huang, J Ye - Journal of Experimental & Clinical Cancer …, 2015 - Springer
Zebrafish represent a vertebrate model organism that has been widely, and increasingly,
employed over the last decade in the study of developmental processes, wound healing …

Polypeptides from traditional Chinese medicine: Comprehensive review of perspective towards cancer management

Z Jia, X Zhu, Y Zhou, J Wu, M Cao, C Hu, L Yu… - International Journal of …, 2024 - Elsevier
Cancer has always been a focus of global attention, and the difficulty of treatment and poor
prognosis have always plagued humanity. Conventional chemotherapeutics and treatment …

[HTML][HTML] Cancer-cell-biomimetic nanoparticles systemically eliminate hypoxia tumors by synergistic chemotherapy and checkpoint blockade immunotherapy

Y Yao, H Chen, N Tan - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Checkpoint blockade-based immunotherapy has shown unprecedented effect in cancer
treatments, but its clinical implementation has been restricted by the low host antitumor …

Irisin attenuates oxidized low‐density lipoprotein impaired angiogenesis through AKT/mTOR/S6K1/Nrf2 pathway

M Zhang, Y Xu, L Jiang - Journal of Cellular Physiology, 2019 - Wiley Online Library
It is known that irisin increases total body energy expenditure, decreases body weight, and
enhances insulin sensitivity. Although previous studies have demonstrated that irisin …

Plant peptides–redefining an area of ribosomally synthesized and post-translationally modified peptides

JR Chekan, LS Mydy, MA Pasquale… - Natural Product …, 2024 - pubs.rsc.org
Covering 1965 to February 2024Plants are prolific peptide chemists and are known to make
thousands of different peptidic molecules. These peptides vary dramatically in their size …

Antimicrobial, antioxidant, and angiogenic bioactive silver nanoparticles produced using Murraya paniculata (L.) jack leaves

P Rama, A Baldelli, A Vignesh… - Nanomaterials and …, 2022 - journals.sagepub.com
Murraya paniculata (MP) can be used as a reducing agent to produce silver nanoparticles
(AgNPs) using a simple procedure. AgNPs are characterized in morphological and chemical …

The research progress of bioactive peptides derived from traditional natural products in China

Y Zhang, L Liu, M Zhang, S Li, J Wu, Q Sun, S Ma… - Molecules, 2023 - mdpi.com
Traditional natural products in China have a long history and a vast pharmacological
repertoire that has garnered significant attention due to their safety and efficacy in disease …

Passive membrane permeability of macrocycles can be controlled by exocyclic amide bonds

JL Hickey, S Zaretsky, MA St. Denis… - Journal of medicinal …, 2016 - ACS Publications
We have developed a strategy for synthesizing passively permeable peptidomimetic
macrocycles. The cyclization chemistry centers on using aziridine aldehydes in a …

Actein Inhibits the Proliferation and Adhesion of Human Breast Cancer Cells and Suppresses Migration in vivo

XX Wu, GGL Yue, JR Dong, CWK Lam… - Frontiers in …, 2018 - frontiersin.org
Background and purpose: Metastasis is an important cause of death in breast cancer
patients. Anti-metastatic agents are urgently needed since standard chemotherapeutics …

Tryptanthrin inhibits angiogenesis by targeting the VEGFR2-mediated ERK1/2 signalling pathway

X Liao, X Zhou, N Mak, K Leung - Plos one, 2013 - journals.plos.org
Angiogenesis is a key step for tumour growth and metastasis, and anti-angiogenesis has
been proposed as an important strategy for cancer therapy. Tryptanthrin is a weakly basic …