Alginate is an edible heteropolysaccharide that abundantly available in the brown seaweed
and the capsule of bacteria such as Azotobacter sp. and Pseudomonas sp. Owing to …

Injuries to articular cartilage and menisci can lead to cartilage degeneration that ultimately
results in arthritis. Different forms of arthritis affect~ 50 million people in the USA alone, and it …

Osteoarthritis (OA), is a major cause of severe joint pain, physical disability and quality of life
impairment in the aging population across the developed and developing world. Increased …

Background Articular cartilage injuries have poor repair capacity, leading to progressive
joint damage, and cannot be restored predictably by either conventional treatments or …

Cell-based therapy represents a promising treatment strategy for cartilage defects. Alone or
in combination with scaffolds/biological signals, these strategies open many new avenues …

Tissue regeneration using stem cell-based transplantation faces many hurdles. Alternatively,
therapeutically exploiting endogenous stem cells to regenerate injured or diseased tissue …

Stem cells and tissue-derived stromal cells stimulate the repair of degenerated and injured
tissues, motivating a growing number of cell-based interventions in the musculoskeletal …

Cartilage tissue engineering has primarily focused on the generation of grafts to repair
cartilage defects due to traumatic injury and disease. However engineered cartilage tissues …

In mature individuals, hyaline cartilage demonstrates a poor intrinsic capacity for repair, thus
even minor defects could result in progressive degeneration, impeding quality of life …

Bioadhesive performance can be compromised due to bleeding. Bleeding increases
mortality. Adhesives with hemostatic function are of great significance. A sustainable and …