Nanoparticles of metal‐organic frameworks: on the road to in vivo efficacy in biomedicine

T Simon‐Yarza, A Mielcarek, P Couvreur… - Advanced …, 2018 - Wiley Online Library
In the past few years, numerous studies have demonstrated the great potential of nano
particles of metal‐organic frameworks (nanoMOFs) at the preclinical level for biomedical …

Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy

M Gao, F Yu, C Lv, J Choo, L Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …

Peptide-drug conjugates and their targets in advanced cancer therapies

P Hoppenz, S Els-Heindl, AG Beck-Sickinger - Frontiers in chemistry, 2020 - frontiersin.org
Cancer became recently the leading cause of death in industrialized countries. Even though
standard treatments achieve significant effects in growth inhibition and tumor elimination …

Poly (2-oxazoline) s based biomaterials: A comprehensive and critical update

T Lorson, MM Luebtow, E Wegener, MS Haider… - Biomaterials, 2018 - Elsevier
Abstract Poly (2-oxazoline) s have been investigated for decades as biomaterials.
Pioneering early work suggested that hydrophilic poly (2-oxazoline) s are comparable to …

Recent advances in targeted drug delivery strategy for enhancing oncotherapy

J Li, Q Wang, G Xia, N Adilijiang, Y Li, Z Hou, Z Fan… - Pharmaceutics, 2023 - mdpi.com
Targeted drug delivery is a precise and effective strategy in oncotherapy that can accurately
deliver drugs to tumor cells or tissues to enhance their therapeutic effect and, meanwhile …

Recent strategies to improve boron dipyrromethene (BODIPY) for photodynamic cancer therapy: an updated review

CS Kue, SY Ng, SH Voon, A Kamkaew… - Photochemical & …, 2018 - Springer
BODIPYs are photosensitizers activatable by light to generate highly reactive singlet oxygen
(1 O 2) from molecular oxygen, leading to tissue damage in the photoirradiated region …

Nanoemulsions in drug delivery: formulation to medical application

HH Tayeb, F Sainsbury - Nanomedicine, 2018 - Taylor & Francis
Nanoscale oil-in-water emulsions (NEs), heterogeneous systems of two immiscible liquids
stabilized by emulsifiers or surfactants, show great potential in medical applications because …

Folate receptor-mediated delivery of mitoxantrone-loaded solid lipid nanoparticles to breast cancer cells

A Granja, C Nunes, CT Sousa, S Reis - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The standard breast cancer therapy still faces major challenges due to non-specific tumor
distribution and occurrence of dose-limiting adverse side-effects. Nanomedicine constitutes …

Peptide ligand-mediated targeted drug delivery of nanomedicines

Z Jiang, J Guan, J Qian, C Zhan - Biomaterials science, 2019 - pubs.rsc.org
Targeted drug delivery is emerging as a promising strategy to achieve better clinical
outcomes. Actively targeted drug delivery that utilizes overexpressed receptors or antigens …

Ultrasmall noble metal nanoparticles: Breakthroughs and biomedical implications

X Jiang, B Du, Y Huang, J Zheng - Nano today, 2018 - Elsevier
As a bridge between individual atoms and large plasmonic nanoparticles, ultrasmall (core
size< 3 nm) noble metal nanoparticles (UNMNPs) have been serving as model for us to …