Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

[HTML][HTML] Crosstalk between the oral microbiota, mucosal immunity, and the epithelial barrier regulates oral mucosal disease pathogenesis

D Lin, L Yang, L Wen, H Lu, Q Chen, Z Wang - Mucosal immunology, 2021 - Elsevier
Oral mucosal disease (OMD), which is also called soft tissue oral disease, is described as a
series of disorders or conditions affecting the mucosa and soft tissue in the oral cavity. Its …

Salivary cytokines as biomarkers for oral squamous cell carcinoma: a systematic review

E Ferrari, ME Pezzi, D Cassi, TA Pertinhez… - International journal of …, 2021 - mdpi.com
The prognosis of patients with oral squamous carcinoma (OSCC) largely depends on the
stage at diagnosis, the 5-year survival rate being approximately 30% for advanced tumors …

Current advances in noninvasive methods for the diagnosis of oral squamous cell carcinoma: a review

S Wang, M Yang, R Li, J Bai - European journal of medical research, 2023 - Springer
Oral squamous cell carcinoma (OSCC), one of the most common types of cancers
worldwide, is diagnosed mainly through tissue biopsy. However, owing to the tumor …

Saliva, a bodily fluid with recognized and potential diagnostic applications

M Boroumand, A Olianas, T Cabras… - Journal of separation …, 2021 - Wiley Online Library
Human whole saliva is a bodily fluid that can be obtained easily by noninvasive techniques.
Specimens can be collected by the patient also at home in order to monitor health status and …

Role of salivary MicroRNA and cytokines in the diagnosis and prognosis of oral squamous cell carcinoma

FJ Manzano-Moreno, VJ Costela-Ruiz… - International journal of …, 2021 - mdpi.com
Oral squamous cell carcinoma (OSCC) is the most prevalent oral malignant tumor
worldwide. An early diagnosis can have a major positive impact on its prognosis. Human …

[HTML][HTML] Salivary biomarkers for early detection of oral squamous cell carcinoma (OSCC) and head/neck squamous cell carcinoma (HNSCC): A systematic review and …

S Khijmatgar, J Yong, N Rübsamen, F Lorusso… - … Dental Science Review, 2024 - Elsevier
Oral cancer became a very common condition. WHO estimates that there are 4 cases of lip
and oral cavity cancer for every 100,000 people worldwide. The early diagnosis of cancers …

Novel impacts of saliva with regard to oral health

H Uchida, CE Ovitt - The journal of prosthetic dentistry, 2022 - Elsevier
The maintenance of balanced oral homeostasis depends on saliva. A readily available and
molecularly rich source of biological fluid, saliva fulfills many functions in the oral cavity …

Salivary miR-31-5p, miR-345-3p, and miR-424-3p are reliable biomarkers in patients with oral squamous cell carcinoma

B Scholtz, J Horváth, I Tar, C Kiss, IJ Márton - Pathogens, 2022 - mdpi.com
If not detected early, oral squamous cell carcinoma (OSCC) has very poor prognosis,
emphasizing the need for reliable early diagnostics. Saliva is considered a promising …

Novel tetrahydrocurcumin integrated mucoadhesive nanocomposite κ-carrageenan/xanthan gum sponges: a strategy for effective local treatment of oral cancerous …

SA Elbanna, HMK Ebada, OY Abdallah… - Drug Delivery, 2023 - Taylor & Francis
Oral cancer is one of the leading causes of death worldwide. Oral precancerous lesions
(OPL) are the precursors of oral cancer, with varying degrees of progression …