Strand-displacing polymerases are a crucial component of isothermal amplification (IA)
reactions, where the lack of thermal cycling reduces equipment needs and improves the …

Adeno-associated virus (AAV) vectors have become one of the most widely used gene
transfer tools in human gene therapy. Considerable effort is currently being focused on AAV …

Protein engineering has emerged as a straightforward and efficient strategy to expand the
application fields of natural enzymes as biocatalysts. It has developed rapidly depending on …

Thermophilic nucleic acid polymerases, isolated from organisms that thrive in extremely hot
environments, possess great DNA/RNA synthesis activities under high temperatures. These …

Disclosed are compositions and methods for nucleic acid amplification and detection.
Specifically, disclosed herein are compositions and methods that allow for amplification of …

Enzymes are extremely complex molecular machines which catalyse with great efficiency a
wide range of chemical reactions. Its catalytic efficiency is, however, limited to certain …