AMP-activated protein kinase (AMPK) is known as a pivotal cellular energy sensor,
mediating the adaptation to low energy levels by deactivating anabolic processes and …

Overweight, obesity, and related diseases are currently the major public health problems
worldwide. Astilbin, extracted from the rhizome of Smilax glabra Roxb., is known to have …

Oxidative stress, inflammatory response, and gut-liver axis dysbiosis have been suggested
as the primarily involved in the pathogenesis of alcoholic liver injury. Previous research …

The metabolic characteristics of COVID-19 disease are still largely unknown. Here, 44
patients with COVID-19 (31 mild COVID-19 patients and 13 severe COVID-19 patients), 42 …

Gemcitabine (GEM) chemotherapy, as the first-line regimen for pancreatic cancer, tends to
induce drug resistance, which ultimately worsens the prognosis of patients with pancreatic …

Hyperoxic conditions are known to accelerate skeletal muscle regeneration after injuries. In
the early phase of regeneration, macrophages invade the injured area and subsequently …

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a complex disease that is
often accompanied by mental health disorders. However, the potential mechanisms …

随着母猪产仔数增加, 仔猪断奶前死亡率也在增加, 严重降低了母猪的繁殖性能.
仔猪初生重是影响仔猪断奶前死亡率的重要因素之一, 而胎盘对调控仔猪初生重尤为重要. 因此 …

Vaskuläre Alterung wird wesentlich durch dysfunktionale Endothelzellen bestimmt, welche
normalerweise die vaskuläre Homöostase aufrechterhalten. Zu den Signalproteinen, die der …

This month's issue of SHOCK will once again feature an outstanding array of papers ranging
from basic science studies to clinical trials, so let's jump into the work. Leonard et al.(1) …