CXCR4 and its ligand CXCL12 mediate the homing of progenitor cells in the bone marrow
and their recruitment to sites of injury, as well as affect processes such as cell arrest …

The pathogenesis of autoimmunity remains to be fully elucidated, although the contribution
of genetic and environmental factors is generally recognized. Despite autoimmune …

Chemokines are small chemotactic molecules that play key roles in physiological and
pathological conditions. Upon signaling via their specific receptors, chemokines regulate …

Multiple sclerosis (MS) is a neurodegenerative autoimmune disease characterized by the
destruction of the myelin sheath of the neuronal axon in the central nervous system. Many …

Background The innate lymphoid cell (ILC) family consists of NK cells, ILC type 1, 2, 3 and
lymphoid tissue inducer cells. They have been shown to play important roles in homeostasis …

The etiology of several autoimmune diseases, including multiple sclerosis (MS) is still not
clarified. MS is defined as an autoimmune disease with clinical features of a chronic …

Stromal cell‐derived factor‐1α (SDF‐1α) has been known to implicate in homing of MSCs,
and resveratrol has been reported to have a positive influence on SDF‐1 level in the site of …

Natural killer (NK) cells are involved in the pathogenesis of inflammatory demyelinating
diseases of the central nervous system. However, the differential expressions of NK cells in …

SDF-1a is a member of CXC chemokine family that plays a crucial role in stem cell
migration, cell apoptosis and development. The role of intra-scrotal administration of SDF-1a …

Multiple sclerosis (MS) is a chronic inflammatory, demyelinating disease that affects the
central nervous system (CNS) resulting in progressive cognitive decline and physical …