Stressing the importance of plant specialized metabolites: omics-based approaches for discovering specialized metabolism in plant stress responses

M Wu, TR Northen, Y Ding - Frontiers in Plant Science, 2023 - frontiersin.org
Plants produce a diverse range of specialized metabolites that play pivotal roles in
mediating environmental interactions and stress adaptation. These unique chemical …

Cell‐type‐specific metabolism in plants

DM Daloso, EG Morais, KF Oliveira e Silva… - The Plant …, 2023 - Wiley Online Library
Every plant organ contains tens of different cell types, each with a specialized function.
These functions are intrinsically associated with specific metabolic flux distributions that …

Exogenous strigolactone (GR24) positively regulates growth, photosynthesis, and improves glandular trichome attributes for enhanced artemisinin production in …

KI Wani, A Zehra, S Choudhary, M Naeem… - Journal of Plant Growth …, 2023 - Springer
Artemisia annua is a medicinal plant particularly known for the production of a
sesquiterpene lactone artemisinin; a specialty metabolite known for its efficacy in the …

Artemisinin production strategies for industrial scale: Current progress and future directions

F Qamar, K Ashrafi, A Singh, PK Dash… - Industrial Crops and …, 2024 - Elsevier
Artemisinin is renowned for its various biological activities, particularly its effectiveness
against malaria. However, its commercial production is impeded by its low accumulation in …

Profiling of phytohormone‐specific microRNAs and characterization of the miR160‐ARF1 module involved in glandular trichome development and artemisinin …

Z Guo, K Hao, Z Lv, L Yu, Q Bu, J Ren… - Plant Biotechnology …, 2023 - Wiley Online Library
MicroRNAs (miRNAs) play crucial roles in plant development and secondary metabolism
through different modes of sequence‐specific interaction with their targets. Artemisinin …

Elevation of artemisinin content by co-transformation of artemisinin biosynthetic pathway genes and trichome-specific transcription factors in Artemisia annua

D Hassani, A Taheri, X Fu, W Qin, L Hang… - Frontiers in Plant …, 2023 - frontiersin.org
Artemisinin, derived from Artemisia annua, is currently used as the first-line treatment for
malaria. However, wild-type plants have a low artemisinin biosynthesis rate. Although yeast …

CbMYB108 integrates the regulation of diterpene biosynthesis and trichome development in Conyza blinii against UV‐B

J Zhan, T Di, X Chen, T Zheng, W Sun… - Plant, Cell & …, 2024 - Wiley Online Library
Plants synthesize abundant terpenes through glandular trichomes (GTs), thereby protecting
themselves from environmental stresses and increasing the economic value in some …

Increased artemisinin production by promoting glandular secretory trichome formation and reconstructing the artemisinin biosynthetic pathway in Artemisia annua

Y Li, W Qin, H Liu, T Chen, X Yan, W He… - Horticulture …, 2023 - academic.oup.com
Dear Editor, Artemisinin, which has potent antimalarial properties, is a sesquiterpene
endoperoxide originally isolated from the traditional Chinese medicinal plant Artemisia …

Biosynthesis and regulation of diterpenoids in medicinal plants

REN Junze, WU Yu, ZHU Zhanpin, C Ruibing… - Chinese Journal of …, 2022 - Elsevier
Plant diterpenoids are widely distributed and abundant natural products with diverse
structures and functions in nature, which have been commonly used in pharmaceutical …

Advanced metabolic engineering strategies for increasing artemisinin yield in Artemisia annua L.

Y Li, Y Yang, L Li, K Tang, X Hao, G Kai - Horticulture Research, 2024 - academic.oup.com
Artemisinin, also known as 'Qinghaosu', is a chemically sesquiterpene lactone containing an
endoperoxide bridge. Due to the high activity to kill Plasmodium parasites, artemisinin and …