Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …

Traumatic brain injury (TBI) is associated with high mortality and disability, with a substantial
socioeconomic burden. With the standardization of the treatment process, there is increasing …

Background Neuroinflammation is one of the most important processes in secondary injury
after traumatic brain injury (TBI). Triggering receptor expressed on myeloid cells 2 (TREM2) …

In this study, we investigated the mechanisms through which astrocyte-derived exosomes
(AS-Exos) alleviate traumatic brain injury (TBI)-induced neuronal defects in TBI model rats …

Tissue engineering biomaterials are aimed to mimic natural tissue and promote new tissue
formation for the treatment of impaired or diseased tissues. Highly porous biomaterial …

Traumatic brain injury (TBI) is a structural and physiological disruption of brain function
caused by external forces. It is a major cause of death and disability for patients worldwide …

Stem cell therapy is promising for neural repair in devastating traumatic brain injury (TBI).
However, the low survival and differentiation rates of transplanted stem cells are main …

Traumatic brain injury (TBI) is a serious disease that threatens life and health of people. It
poses a great economic burden on the healthcare system. Thus, seeking effective therapy to …

Background Large-scale studies are required to better characterise traumatic brain injury
(TBI) and to identify the most effective treatment approaches for TBI. However, evidence is …

Traumatic brain injury (TBI) is one of the most devastating nervous injuries. Neural tissue
engineering based on stem cells and bioactive scaffold is a promising but challenging …