[HTML][HTML] Inhibition of the main protease of SARS-CoV-2 (Mpro) by repurposing/designing drug-like substances and utilizing nature's toolbox of bioactive compounds
The emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
has resulted in a long pandemic, with numerous cases and victims worldwide and enormous …
has resulted in a long pandemic, with numerous cases and victims worldwide and enormous …
Docking and in silico toxicity assessment of Arthrospira compounds as potential antiviral agents against SARS-CoV-2
L Petit, L Vernès, JP Cadoret - Journal of applied phycology, 2021 - Springer
A race is currently being launched as a result of the international health situation. This race
aims to find, by various means, weapons to counter the Covid-19 pandemic now widespread …
aims to find, by various means, weapons to counter the Covid-19 pandemic now widespread …
An in-silico pharmacophore-based molecular docking study to evaluate the inhibitory potentials of novel fungal triterpenoid Astrakurkurone analogues against a …
Background The main protease is an important structural protein of SARS-CoV-2, essential
for its survivability inside a human host. Considering current vaccines' limitations and the …
for its survivability inside a human host. Considering current vaccines' limitations and the …
Docking-based evidence for the potential of ImmunoDefender: A novel formulated essential oil blend incorporating synergistic antiviral bioactive compounds as …
A Ksouri, A Klouz, B Bouhaouala-Zahar, F Moussa… - Molecules, 2023 - mdpi.com
Essential oils (Eos) have demonstrated antiviral activity, but their toxicity can hinder their use
as therapeutic agents. Recently, some essential oil components have been used within safe …
as therapeutic agents. Recently, some essential oil components have been used within safe …
An Overview on Immunity Booster Foods in Coronavirus Disease (COVID-19)
The present COVID-19 pandemic is terrible for the respiratory system and is caused by
severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). It has affected millions of …
severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). It has affected millions of …
Exploring Antioxidant and α-Glucosidase Inhibitory Activities in Mulberry Leaves (Morus alba L.) across Growth Stages: A Comprehensive Metabolomic Analysis with …
W Li, S Hao, H Li, Q An, L Yang, B Guo, Z Xue, Y Liu… - Molecules, 2023 - mdpi.com
Metabolic product accumulation exhibited variations among mulberry (Morus alba L.) leaves
(MLs) at distinct growth stages, and this assessment was conducted using a combination of …
(MLs) at distinct growth stages, and this assessment was conducted using a combination of …
An investigation of binding interactions of tumor-targeted peptide conjugated polyphenols with the kinase domain of ephrin B4 and B2 receptors
SM Mitchell, RM Heise, ME Murray, DJ Lambo… - Molecular Diversity, 2024 - Springer
Recent studies have shown that Ephrin receptors may be upregulated in several types of
cancers including breast, ovarian and endometrial cancers, making them a target for drug …
cancers including breast, ovarian and endometrial cancers, making them a target for drug …
Molecular dynamic simulations to explore the broad-spectrum activity of the inhibitor PF-07321332 against human coronavirus
MT Liu, YT Wang, Y Li, P Sang… - Journal of Biomolecular …, 2024 - Taylor & Francis
The main protease (Mpro) stands as a pivotal enzyme crucial for coronavirus replication,
thus serving as a prime target for coronavirus drug discovery endeavors. Nirmatrelvir (PF …
thus serving as a prime target for coronavirus drug discovery endeavors. Nirmatrelvir (PF …
Bioinformatics Study of Flavonoids From Genus Erythrina As Ace2 inhibitor Candidates For Covid-19 Treatment
Purpose This study aimed to screen potential drug candidates from the flavonoids of the
genus Erythrina for the Corona Virus Disease 2019 (COVID-19) treatment. Patients and …
genus Erythrina for the Corona Virus Disease 2019 (COVID-19) treatment. Patients and …
Spices for taming the COVID-19 pandemic: Prospects and perspectives
SJ Eapen - 2021 - 14.139.189.23
Coronavirus Disease 2019 (COVID-19), first reported in December 2019 from Wuhan in
China, had reached the stage of a pandemic. To date (28.06. 2021), there are more than …
China, had reached the stage of a pandemic. To date (28.06. 2021), there are more than …