DUSP2 recruits CSNK2A1 to suppress AKT1-mediated apoptosis resistance under hypoxic microenvironment in pancreatic cancer
Y Zhang, R Kong, W Yang, K Hu, Z Zhao, L Li, X Geng… - Cancer Letters, 2023 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxic tumor
microenvironment (TME), which aids tumor progression, drug resistance, and immune …
microenvironment (TME), which aids tumor progression, drug resistance, and immune …
Diabetes Driven Oncogenesis and Anticancer Potential of Repurposed Antidiabetic Drug: A Systemic Review
Diabetes and cancer are two prevalent disorders, pose significant public health challenges
and contribute substantially to global mortality rates, with solely 10 million reported cancer …
and contribute substantially to global mortality rates, with solely 10 million reported cancer …
Calycosin ameliorates spinal cord injury by targeting Hsp90 to inhibit oxidative stress and apoptosis of nerve cells
M Li, Y Huan, X Wang, M Tao, T Jiang, H Xie… - Journal of Chemical …, 2023 - Elsevier
Background Zhenbao pill is effective in protecting against spinal cord injury (SCI). We
attempt to explore the characteristics of calycosin (a main monomer of Zhenbao pill) in SCI …
attempt to explore the characteristics of calycosin (a main monomer of Zhenbao pill) in SCI …
ACA‐28, an ERK MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic Cancer Cells
T Takasaki, Y Hamabe, K Touchi… - Oxidative Medicine …, 2024 - Wiley Online Library
The extracellular signal‐regulated kinase (ERK) MAPK pathway is dysregulated in various
human cancers and is considered an attractive therapeutic target for cancer. Therefore …
human cancers and is considered an attractive therapeutic target for cancer. Therefore …
Nuclear receptor coactivator 6 (NCoA6) promotes cell proliferation, migration, and invasion in pancreatic cancer
X Wang, Y Jia, X Xu, Y Hu, G Fan, D Jing… - Cancer …, 2023 - Wiley Online Library
Abstract Background Nuclear receptor coactivator 6 (NCoA6) is overexpressed in various
cancers and considered a multifunctional coactivator of various transcription factors and …
cancers and considered a multifunctional coactivator of various transcription factors and …
ACAGT‐007a, an anti‐cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells
GI Khandakar, Y Miyamoto, R Satoh… - Genes to …, 2023 - Wiley Online Library
The extracellular‐signal‐regulated‐kinase (ERK) signaling pathway is essential for cell
proliferation and is frequently deregulated in human tumors such as pancreatic cancers …
proliferation and is frequently deregulated in human tumors such as pancreatic cancers …
[HTML][HTML] ACA-28, an anticancer compound, induces Pap1 nuclear accumulation via ROS-dependent and-independent mechanisms in fission yeast
T Takasaki, R Obana, D Fujiwara… - Micropublication …, 2023 - ncbi.nlm.nih.gov
The nucleocytoplasmic transport of proteins is an important mechanism to control cell fate.
Pap1 is a fission yeast nucleocytoplasmic shuttling transcription factor of which localization …
Pap1 is a fission yeast nucleocytoplasmic shuttling transcription factor of which localization …
Pankreas Kanserinde Susturulan Tuft1 Geninin Mapk Yolağı ve Pd-l1 Geni Üzerine Etkilerinin İn Vitro Olarak İncelenmesi
G Türkoğlu - 2023 - acikerisim.selcuk.edu.tr
Özet Pankreas kanseri, geç tanı ve kemoradyoterapiye direnci nedeniyle çok kötü prognoza
sahip en agresif malignitelerden biridir. Bu nedenle, daha etkili, spesifik terapiler ve ilgili …
sahip en agresif malignitelerden biridir. Bu nedenle, daha etkili, spesifik terapiler ve ilgili …