A novel nasal almotriptan loaded solid lipid nanoparticles in mucoadhesive in situ gel formulation for brain targeting: preparation, characterization and in vivo …

NAH Abou Youssef, AA Kassem, RM Farid… - International journal of …, 2018 - Elsevier
This work aimed at designing efficient safe delivery system for intranasal (IN) brain targeting
of the water soluble anti-migraine drug Almotriptan malate (ALM). Solid lipid nanoparticles …

Coated lipidic nanoparticles as a new strategy for enhancing nose-to-brain delivery of a hydrophilic drug molecule

LH Salem, GS El-Feky, RH Fahmy… - Journal of …, 2020 - Elsevier
Oral Almotriptan maleate (ALM) is used in the treatment of migraine; however, due to its
extreme aqueous solubility, shows poor penetration and lesser concentration in the brain …

Fluorescence-based method for sensitive and rapid estimation of chlorin e6 in stealth liposomes for photodynamic therapy against cancer

R Jain, R Pradhan, S Hejmady, G Singhvi… - Spectrochimica Acta Part …, 2021 - Elsevier
Chlorin e6 is a chlorine-based porphyrin containing photosensitizer mainly used for the
therapy in cancers like neck and head, early-stage lung cancer, and topical skin cancers …

Illuminating the analytical chemistry Profile: A Three-Decade comprehensive review of fluorometric quantitation in pharmaceutical formulations

R Kotadiya - Microchemical Journal, 2024 - Elsevier
Owing to its high sensitivity and specificity, fluorescence spectroscopy has emerged as a
critical analytical tool for pharmaceutical formulations. Over the last three decades, it has …

Magnetic solid phase extraction of rizatriptan in human urine samples prior to its spectrofluorimetric determination

M Soleimani, M Ahmadi, T Madrakian… - Sensors and Actuators B …, 2018 - Elsevier
A method has been developed and validated for the determination of rizatriptan drug in
human urine samples. Magnetic solid phase extraction (MSPE) utilizing a molecularly …

Vortex-assisted dispersive solid phase microextraction using Fe3O4/FeOOH magnetic nanocomposites for high-performance thin-layer chromatographic …

PY Khashaba, AH Rageh, NN Atia… - Journal of Chromatography …, 2021 - Elsevier
In this work, a fast, versatile, and convenient dispersive solid-phase micro-extraction
(DSPME) method is combined with a spectro-densitometric technique for the analysis of …

[PDF][PDF] Validation of rapid and sensitive spectrofluorimetric assay for determination of four triptans in pure and dosage forms; application to human plasma and content …

M Hammad, M Omar, W Eltoukhi - Pharm. Anal. Acta, 2016 - researchgate.net
A sensitive, simple, rapid and reliable spectrofluorimetric assay was developed for the assay
of definite antimigraine drugs namely; Almotriptan malate, Rizatriptan benzoate, Sumatriptan …

QuEChERS-assisted ion pair chromatography/fluorescence detection method for determination of antimigraine combination therapy in rabbit plasma samples …

AH Rageh, PY Khashaba, SA El Zohny… - Journal of Pharmaceutical …, 2023 - Elsevier
Antimigraine combination therapy has shown significant effectiveness in relieving pain, as
well as reducing the frequency, duration, and severity of migraine attacks if compared to a …

Spectrophotometric Determination of Certain Antimigraine Drugs in Pharmaceutical Formulations Using p-Chloranil Reagent; Application to Content Uniformity …

MA Omar, MA Hammad, WE Eltoukhi - Analytical Chemistry Letters, 2017 - Taylor & Francis
A sensitive, simple and reliable spectrophotometric method has been developed for
determination of definite anti-migraine drugs namely; Almotriptan malate, Rizatriptan …

Novel spectrofluorimetric assessment of ondansetron hydrochloride based on excited state quenching of pararosaniline fluorophore

AA Essawy, HM Ali - Journal of the Taiwan Institute of Chemical Engineers, 2018 - Elsevier
In this work, pararosaniline hydrochloride (PA) was developed as the first fluorescent probe
used for the spectrofluorimetric determination of ondansetron (OND). The analytical method …