Alzheimer's disease (AD) is a devastating neurodegenerative disorder without a cure. Most
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …

Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …

Mitochondrial abnormalities have been identified as a central mechanism in multiple
neurodegenerative diseases and, therefore, the mitochondria have been explored as a …

Alzheimer's Disease (AD) currently affects more than 5 million Americans, with numbers
expected to grow dramatically as the population ages. The pathophysiological changes in …

Alzheimer's disease (AD) is characterized by the progressive degeneration of neuronal
cells. With the increase in aged population, there is a prevalence of irreversible …

Ferroptosis is a unique form of programmed death, characterised by cytosolic accumulation
of iron, lipid hydroperoxides and their metabolites, and effected by the fatal peroxidation of …

Several melatonin receptors agonists (ramelteon, prolonged-release melatonin,
agomelatine and tasimelteon) have recently become available for the treatment of insomnia …

Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mainly the memory
and cognitive function in elderly. Extracellular beta amyloid deposition and intracellular tau …

Mitochondria are crucial organelles as their role in cellular energy production of eukaryotes.
Because the brain cells demand high energy for maintaining their normal activities …

Alzheimer's disease (AD) is an increasingly pressing worldwide public-health, social,
political and economic concern. Despite significant investment in multiple traditional …