Classification, diagnosis, and differential diagnosis of multiple sclerosis

IK Sand - Current opinion in neurology, 2015 - journals.lww.com
Current multiple sclerosis phenotypic classifications include relapsing-remitting multiple
sclerosis, clinically isolated syndrome, radiologically isolated syndrome, primary …

The cerebrospinal fluid in multiple sclerosis

F Deisenhammer, H Zetterberg, B Fitzner… - Frontiers in …, 2019 - frontiersin.org
Investigation of cerebrospinal fluid (CSF) in the diagnostic work-up in suspected multiple
sclerosis (MS) patients has regained attention in the latest version of the diagnostic criteria …

The diagnosis of multiple sclerosis and the various related demyelinating syndromes: a critical review

D Karussis - Journal of autoimmunity, 2014 - Elsevier
Multiple sclerosis (MS), is a chronic disease of the central nervous system (CNS)
characterized by loss of motor and sensory function, that results from immune-mediated …

The evolution of neurofilament light chain in multiple sclerosis

C Ferreira-Atuesta, S Reyes, G Giovanonni… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune, inflammatory neurodegenerative disease of the
central nervous system characterized by demyelination and axonal damage. Diagnosis and …

Neurofilament light chain as a biomarker in multiple sclerosis

KN Varhaug, Ø Torkildsen, KM Myhr… - Frontiers in …, 2019 - frontiersin.org
Due to the unpredictable course and heterogenous treatment response in multiple sclerosis
(MS), there is a clear need for biomarkers that reflect disease activity in the clinical follow-up …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Neuronal and glial CSF biomarkers in multiple sclerosis: A systematic review and meta-analysis

S Momtazmanesh, P Shobeiri… - Reviews in the …, 2021 - degruyter.com
Multiple sclerosis (MS) is a neurodegenerative disease associated with inflammatory
demyelination and astroglial activation, with neuronal and axonal damage as the leading …

Body fluid biomarkers for multiple sclerosis—the long road to clinical application

CE Teunissen, A Malekzadeh, C Leurs… - Nature Reviews …, 2015 - nature.com
There is a strong unmet clinical need for objective body fluid biomarkers to assist early
diagnosis and estimate long-term prognosis, monitor treatment response and predict …

Neurofilament light chain level is a weak risk factor for the development of MS

G Arrambide, C Espejo, H Eixarch, LM Villar… - Neurology, 2016 - AAN Enterprises
Objective: To determine the prognostic value of selected biomarkers in clinically isolated
syndromes (CIS) for conversion to multiple sclerosis (MS) and disability accrual. Methods …

Cerebrospinal fluid neurofilament light chain in multiple sclerosis and its subtypes: a meta-analysis of case–control studies

SJ Martin, S McGlasson, D Hunt… - Journal of Neurology …, 2019 - jnnp.bmj.com
Objective Neurofilament is a biomarker of axonal injury proposed as a useful adjunct in the
monitoring of patients with multiple sclerosis (MS). We conducted a systematic review and …