Know your enemy: successful bioinformatic approaches to predict functional RNA structures in viral RNAs
Structured RNA elements may control virus replication, transcription and translation, and
their distinct features are being exploited by novel antiviral strategies. Viral RNA elements …
their distinct features are being exploited by novel antiviral strategies. Viral RNA elements …
Structural and computational studies of HIV-1 RNA
L Levintov, H Vashisth - RNA biology, 2024 - Taylor & Francis
Viruses remain a global threat to animals, plants, and humans. The type 1 human
immunodeficiency virus (HIV-1) is a member of the retrovirus family and carries an RNA …
immunodeficiency virus (HIV-1) is a member of the retrovirus family and carries an RNA …
CCR5 RNA Pseudoknots: Residue and Site‐Specific Labeling correlate Internal Motions with microRNA Binding
B Chen, AP Longhini, F Nußbaumer… - … A European Journal, 2018 - Wiley Online Library
Conformational dynamics of RNA molecules play a critical role in governing their biological
functions. Measurements of RNA dynamic behavior sheds important light on sites that …
functions. Measurements of RNA dynamic behavior sheds important light on sites that …
NMR studies of retroviral genome packaging
Nearly all retroviruses selectively package two copies of their unspliced RNA genomes from
a cellular milieu that contains a substantial excess of non-viral and spliced viral RNAs. Over …
a cellular milieu that contains a substantial excess of non-viral and spliced viral RNAs. Over …
The Fight against Human Viruses: How NMR Can Help?
M Vincenzi, M Leone - Current Medicinal Chemistry, 2021 - benthamdirect.com
Background: COVID-19 has brought the world to its knees, and there is an urgent need for
new strategies to identify molecules capable of fighting the pandemic. During the last few …
new strategies to identify molecules capable of fighting the pandemic. During the last few …
Insights into Mason-Pfizer monkey virus (MPMV) genomic RNA packaging: Identification of minimal structural motifs involved during its selective encapsidation
MA Lizna - 2021 - search.proquest.com
A distinguishing feature of the Mason-Pfizer monkey virus (MPMV) packaging signalRNA
secondary structure is a single-stranded purine-rich sequence (ssPurines; UITU 191 …
secondary structure is a single-stranded purine-rich sequence (ssPurines; UITU 191 …
RNA Structural Regulation of Reverse Transcription Initiation in HIV
AT Coey - 2018 - search.proquest.com
The process of reverse transcription in HIV is a crucial early step in the viral replication cycle
and must take place before infection is complete. During this process, the viral single …
and must take place before infection is complete. During this process, the viral single …