Cerebrospinal fluid: A specific biofluid for the biosensing of Alzheimer's diseases biomarkers

A Mirzaie, H Nasrollahpour, B Khalilzadeh… - TrAC Trends in …, 2023 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder with an
irreversible, progressive, and untreatable nature that causes progressive deterioration, loss …

Plasmonic nanoparticles as optical sensing probes for the detection of alzheimer's disease

MP Oyarzún, A Tapia-Arellano, P Cabrera… - Sensors, 2021 - mdpi.com
Alzheimer's disease (AD), considered a common type of dementia, is mainly characterized
by a progressive loss of memory and cognitive functions. Although its cause is multifactorial …

Machine learning-assisted pattern recognition of amyloid beta aggregates with fluorescent conjugated polymers and graphite oxide electrostatic complexes

H Wang, M Chen, Y Sun, L Xu, F Li, J Han - Analytical Chemistry, 2022 - ACS Publications
Five fluorescent positively charged poly (para-aryleneethynylene)(P1–P5) were designed to
construct electrostatic complexes C1–C5 with negatively charged graphene oxide (GO). The …

Carbon dots sensitized lanthanide infinite coordination polymer nanoparticles: Towards ratiometric fluorescent sensing of cerebrospinal Aβ monomer as a biomarker …

C Liu, D Lu, X You, G Shi, J Deng, T Zhou - Analytica Chimica Acta, 2020 - Elsevier
Herein, a novel ratiometric fluorescent probe based on CDs@ Eu/GMP ICP nanoparticles
was developed for the detection of Aβ monomer in rat as a biomarker for Alzheimer's …

Diverse reactivity to hypochlorite and copper ions based on a novel Schiff base derived from vitamin B6 cofactor

X Li, Q Wen, J Gu, W Liu, Q Wang, G Zhou… - Journal of Molecular …, 2020 - Elsevier
A new Schiff base receptor (2-amino-3-(((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)
methylene) amino) maleonitrile (GAL)) has been synthesized and such diaminomaleonitrile …

Strategies for measuring concentrations and forms of amyloid-β peptides

H Shen, K Liu, F Kong, M Ren, X Wang… - Biosensors and …, 2024 - Elsevier
Alzheimer's disease (AD) is affecting more and more people worldwide without the effective
treatment, while the existed pathological mechanism has been confirmed barely useful in …

Viscosity measurement sensor: A prototype for a novel medical diagnostic method based on quartz crystal resonator

A Miranda-Martínez, MX Rivera-González, M Zeinoun… - Sensors, 2021 - mdpi.com
Viscosity variation in human fluids, such as Synovial Fluid (SF) or Cerebrospinal Fluid
(CSF), can be used as a diagnostic factor; however, the sample volume obtained for …

Study of new applications of the Quartz Crystal Resonator (QCR) for the characterization of viscoelastic properties of biological fluids of interest for medical …

A Miranda Martínez - 2022 - oa.upm.es
Quartz crystal resonators (QCRs) are widely used as sensors because of their ability to
detect changes in the physical properties of the sample placed on their surface. In addition …

Rod-like amphiphilic AIE-active NIR probe enables super-early precise in-vivo detection of Aβ fibrils/plaques

Y Wang, D Mei, X Zhang, DH Qu, J Mei, H Tian - 2021 - researchsquare.com
Precise and early detection of Aβ fibrils/plaques is pivotal to the diagnosis and treatment of
Alzheimer's disease (AD), a serious disease threatening human health. Optical imaging …

Rationally Designing Simple Rod-Like Amphiphilic NIR-Emissive AIE Probes for Precise In-Vivo Detection of Aβ Fibrils/Plaques at A Super-Early Stage

Y Wang, D Mei, X Zhang, DH Qu, J Mei, H Tian - 2021 - chemrxiv.org
With increase of social aging, Alzheimer's disease (AD) has been one of the serious
diseases threatening human health. The occurrence of Aβ fibrils or plaques is recognized as …