Metabolism, metabolites, and macrophages in cancer

M Li, Y Yang, L Xiong, P Jiang, J Wang, C Li - Journal of hematology & …, 2023 - Springer
Tumour-associated macrophages (TAMs) are crucial components of the tumour
microenvironment and play a significant role in tumour development and drug resistance by …

[HTML][HTML] Targeted nanomedicines remodeling immunosuppressive tumor microenvironment for enhanced cancer immunotherapy

Y Xu, J Xiong, X Sun, H Gao - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Cancer immunotherapy has significantly flourished and revolutionized the limited
conventional tumor therapies, on account of its good safety and long-term memory ability …

Recent developments in application of single-cell RNA sequencing in the tumour immune microenvironment and cancer therapy

PH Li, XY Kong, YZ He, Y Liu, X Peng, ZH Li… - Military Medical …, 2022 - Springer
The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour
immune microenvironment (TIME). This review focuses on the application of scRNA-seq in …

Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

[HTML][HTML] A comprehensive review on the composition, biogenesis, purification, and multifunctional role of exosome as delivery vehicles for cancer therapy

J Li, Y Zhang, PY Dong, GM Yang… - Biomedicine & …, 2023 - Elsevier
All forms of life produce nanosized extracellular vesicles called exosomes, which are
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …

c-MYC mediates the crosstalk between breast cancer cells and tumor microenvironment

F Gao, X Li, K Xu, R Wang, X Guan - Cell Communication and Signaling, 2023 - Springer
The MYC oncogenic family is dysregulated in diverse tumors which is generally linked to the
poor prognosis of tumors. The members in MYC family are transcription factors which are …

The promising role of tumor-associated macrophages in the treatment of cancer

H Wang, X Wang, X Zhang, W Xu - Drug Resistance Updates, 2024 - Elsevier
Macrophages are important components of the immune system. Mature macrophages can
be recruited to tumor microenvironment that affect tumor cell proliferation, invasion and …

Roles for macrophage-polarizing interleukins in cancer immunity and immunotherapy

K Mortezaee, J Majidpoor - Cellular Oncology, 2022 - Springer
Macrophages are the most abundant and one of the most critical cells of tumor immunity.
They provide a bridge between innate and adaptive immunity through releasing cytokines …

Role of glucose metabolic reprogramming in breast cancer progression and drug resistance

P Lei, W Wang, M Sheldon, Y Sun, F Yao, L Ma - Cancers, 2023 - mdpi.com
Simple Summary Glucose metabolic reprogramming is a process in which cells alter the way
that glucose is utilized. In breast cancer, cells can undergo this process to fuel their growth …

The immune landscape of breast cancer: strategies for overcoming immunotherapy resistance

K Retecki, M Seweryn, A Graczyk-Jarzynka, M Bajor - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy is a rapidly advancing field in breast cancer treatment,
however, it encounters many obstacles that leave open gateways for breast cancer cells to …