Chemoresistance is a major factor driving tumour relapse and the high rates of cancer-
related deaths. Understanding how cancer cells overcome chemotherapy-induced cell …

Over the past years, it has become evident that cancer initiation and progression depends
on several components of the tumor microenvironment, including inflammatory and immune …

Plant secretomics is a newly emerging area of the plant proteomics field. It basically
describes the global study of secreted proteins into the extracellular space of plant cell or …

“Secretome” is referred to as the rich, complex set of molecules secreted from living cells. In
a less strict definition frequently followed in “secretome” studies, the term also includes …

The proteins secreted by various cells (the secretomes) are a potential rich source of
biomarkers as they reflect various states of the cells at real time and at given conditions. To …

The scavenger receptor cysteine-rich (SRCR) superfamily of soluble or membrane-bound
protein receptors is characterized by the presence of one or several repeats of an ancient …

Within a mammalian organism, the interaction among cells both at short and long distances
is mediated by soluble factors released by cells into the extracellular environment. The …

Intracellular membrane protein trafficking is crucial for both normal cellular physiology and
cell-cell communication. The conventional secretory route follows transport from the …

Although cancer cell secretome profiling is a promising strategy used to identify potential
body fluid-accessible cancer biomarkers, questions remain regarding the depth to which the …

In the strictest sense, the cell secretome (conditioned media) refers to the collection of
proteins that contain a signal peptide and are processed via the endoplasmic reticulum and …