Establishment of In Vitro Dissolution Based on Similarity with In Vivo Dissolution: A Case Study on Aripiprazole
In vitro dissolution that predicts the in vivo performance of solid preparations is extremely
important in formulation optimization. Fraction absorbed (F a) has been used to screen in …
important in formulation optimization. Fraction absorbed (F a) has been used to screen in …
Investigation of patient-centric 3D-printed orodispersible films containing amorphous aripiprazole
The objective of this study was to design and evaluate an orodispersible film (ODF)
composed of aripiprazole (ARP), prepared using a conventional solvent casting technique …
composed of aripiprazole (ARP), prepared using a conventional solvent casting technique …
Multicomponent crystalline solid forms of aripiprazole produced via hot melt extrusion techniques: An exploratory study
A Butreddy, M Almutairi, N Komanduri… - Journal of drug delivery …, 2021 - Elsevier
Multicomponent crystalline solid forms (salts, cocrystals and eutectics) are a promising
means of enhancing the dissolution behavior of poorly soluble drugs. The present study …
means of enhancing the dissolution behavior of poorly soluble drugs. The present study …
In Vitro and In Vivo testing of 3D-Printed Amorphous Lopinavir Printlets by Selective Laser Sinitering: Improved Bioavailability of a Poorly Soluble Drug
The aim of this paper was to investigate the effects of formulation parameters on the
physicochemical and pharmacokinetic (PK) behavior of amorphous printlets of lopinavir …
physicochemical and pharmacokinetic (PK) behavior of amorphous printlets of lopinavir …