BK polyomavirus: clinical aspects, immune regulation, and emerging therapies

GR Ambalathingal, RS Francis, MJ Smyth… - Clinical microbiology …, 2017 - Am Soc Microbiol
SUMMARY BK polyomavirus (BKV) causes frequent infections during childhood and
establishes persistent infections within renal tubular cells and the uroepithelium, with …

ECIL guidelines for the prevention, diagnosis and treatment of BK polyomavirus-associated haemorrhagic cystitis in haematopoietic stem cell transplant recipients

S Cesaro, T Dalianis… - Journal of …, 2018 - academic.oup.com
Objectives To define guidelines for BK polyomavirus (BKPyV)-associated haemorrhagic
cystitis (BKPyV-HC) after paediatric and adult HSCT. Methods Review of English literature …

Posoleucel, an allogeneic, off-the-shelf multivirus-specific T-cell therapy, for the treatment of refractory viral infections in the post-HCT setting

T Pfeiffer, I Tzannou, M Wu, C Ramos, G Sasa… - Clinical Cancer …, 2023 - AACR
Purpose: Viral infections are a major cause of morbidity and mortality following allogeneic
hematopoietic cell transplantation (allo-HCT). In the absence of safe and effective antiviral …

[HTML][HTML] The role of polyomaviruses in human disease

M Jiang, JR Abend, SF Johnson, MJ Imperiale - Virology, 2009 - Elsevier
The human polyomaviruses, BK virus and JC virus, have long been associated with serious
diseases including polyomavirus nephropathy and progressive multifocal …

Polyomavirus BK infection in blood and marrow transplant recipients

LK Dropulic, RJ Jones - Bone marrow transplantation, 2008 - nature.com
The association of BK virus infection with hemorrhagic cystitis in blood and marrow
transplant (BMT) recipients was first demonstrated two decades ago. During this time …

[HTML][HTML] BK polyomavirus: emerging pathogen

SM Bennett, NM Broekema, MJ Imperiale - Microbes and infection, 2012 - Elsevier
BK polyomavirus (BKPyV) is a small double-stranded DNA virus that is an emerging
pathogen in immunocompromised individuals. BKPyV is widespread in the general …

[HTML][HTML] Infectious complications after hematopoietic stem cell transplantation: current status and future perspectives in Korea

SY Cho, HJ Lee, DG Lee - The Korean journal of internal medicine, 2018 - ncbi.nlm.nih.gov
Hematopoietic stem cell transplantation (HSCT) is a treatment for hematologic malignancies,
immune deficiencies, or genetic diseases, ect. Recently, the number of HSCTs performed in …

Cidofovir for BK virus-associated hemorrhagic cystitis: a retrospective study

S Cesaro, HH Hirsch, M Faraci… - Clinical infectious …, 2009 - academic.oup.com
Background. BK virus-associated hemorrhagic cystitis (BKV-HC) is a severe complication
after allogeneic hematopoietic stem cell transplantation (HSCT), but antiviral treatment for …

[HTML][HTML] Cidofovir in the treatment of BK virus–associated hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation

M Philippe, F Ranchon, L Gilis, V Schwiertz… - Biology of Blood and …, 2016 - Elsevier
After allogeneic hematopoietic stem cell transplantation (HSCT), BK virus–associated
hemorrhagic cystitis (BKV-HC) is a common complication. Although supportive measures …

Human polyomavirus reactivation: disease pathogenesis and treatment approaches

CF De Gascun, MJ Carr - Journal of Immunology Research, 2013 - Wiley Online Library
JC and BK polyomaviruses were discovered over 40 years ago and have become
increasingly prevalent causes of morbidity and mortality in a variety of distinct …