The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …

Natural products have served as powerful therapeutics against pathogenic bacteria since
the golden age of antibiotics of the mid-20th century. However, the increasing frequency of …

Antimicrobial resistance constitutes one of the major challenges facing humanity in the
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …

Quorum sensing (QS), a microbial cell-to-cell communication process, dynamically regulates
a variety of metabolism and physiological activities. In this review, we provide an update on …

Quorum sensing (QS) is a cell-cell communication mechanism that connects members in
various microbial systems. Conventionally, a small number of QS entries are collected for …

The ribosomally synthesized and posttranslationally modified peptides (RiPPs), also called
ribosomal peptide natural products (RPNPs), form a growing superfamily of natural products …

Bacteria adapt to changes in their environment using a mechanism known as the two-
component regulatory system (TCS)(also called “two-component signal transduction system” …

Biofilms are complex microbial architectures that encase microbial cells in a matrix
comprising self-produced extracellular polymeric substances. Microorganisms living in …

In Gram-positive bacteria such as Staphylococcus aureus and the coagulase-negative
staphylococci (CoNS), the accessory gene regulator (agr) is a highly conserved but …

Recent studies highlight the abundance of commensal co agulase-n egative s taphylococci
(CoNS) on healthy skin. Evidence suggests that CoNS actively shape the skin …