Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy

M Gao, F Yu, C Lv, J Choo, L Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …

Ligand-targeted drug delivery

M Srinivasarao, PS Low - Chemical reviews, 2017 - ACS Publications
Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …

Antimicrobial peptides–Advances in development of therapeutic applications

HX Luong, TT Thanh, TH Tran - Life sciences, 2020 - Elsevier
The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …

[HTML][HTML] Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects

A Sultana, M Zare, V Thomas, TSS Kumar… - Medicine in Drug …, 2022 - Elsevier
Drug delivery can be defined as the group of approaches a drug or pharmacologically active
agent can be transported to the target cell to treat disease or health issue. Conventional …

BODIPY-based probes for the fluorescence imaging of biomolecules in living cells

T Kowada, H Maeda, K Kikuchi - Chemical Society Reviews, 2015 - pubs.rsc.org
Fluorescence imaging techniques have been widely used to visualize biological molecules
and phenomena. In particular, several studies on the development of small-molecule …

Linkers: An assurance for controlled delivery of antibody-drug conjugate

R Sheyi, BG de la Torre, F Albericio - Pharmaceutics, 2022 - mdpi.com
As one of the major therapeutic options for cancer treatment, chemotherapy has limited
selectivity against cancer cells. Consequently, this therapeutic strategy offers a small …

Improving cellular uptake of therapeutic entities through interaction with components of cell membrane

R Zhang, X Qin, F Kong, P Chen, G Pan - Drug Delivery, 2019 - Taylor & Francis
Efficient cellular delivery of biologically active molecules is one of the key factors that affect
the discovery and development of novel drugs. The plasma membrane is the first barrier that …

Mechanisms of drug release in nanotherapeutic delivery systems

PT Wong, SK Choi - Chemical reviews, 2015 - ACS Publications
Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …

Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity

DS Wilson, S Hirosue, MM Raczy, L Bonilla-Ramirez… - Nature materials, 2019 - nature.com
Fully effective vaccines for complex infections must elicit a diverse repertoire of antibodies
(humoral immunity) and CD8+ T-cell responses (cellular immunity). Here, we present a …