Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …

Vaccines are one of the most powerful technologies supporting public health. The adaptive
immune response induced by immunization arises following appropriate activation and …

Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

The immune system is one of the most important, complex biological networks regulating
and protecting human health. Its precise modulation can prevent deadly infections and fight …

This article reviews the state-of-the art in responsive polymer systems for controlled drug
delivery applications. The paper describes different types of stimuli-sensitive systems and …

Microparticles offer various significant advantages as drug delivery systems, including:(i) an
effective protection of the encapsulated active agent against (eg enzymatic) degradation,(ii) …

Rational materials design based on prior knowledge is attractive because it promises to
avoid time-consuming synthesis and testing of numerous materials candidates. However …

In the treatment of health related dysfunctions, it is desirable that the drug reaches its site of
action at a particular concentration and that this therapeutic dose range remains constant …

Injectable matrices and depots have been the subject of much research in the field of drug
delivery. The classical tissue engineering paradigm includes a matrix or scaffold to facilitate …