Benzimidazole–Oxadiazole Hybrids—Development in Medicinal Chemistry: An Overview
RM Bhat, V Hegde, S Budagumpi… - Chemical Biology & …, 2024 - Wiley Online Library
To increase the success rate of drug discovery, one practical strategy is to begin molecular
hybridisation. The presence of two or more pharmacophores in a single unit leads to a …
hybridisation. The presence of two or more pharmacophores in a single unit leads to a …
Azole Derivatives: Cutting‐Edge Agents in Cancer Therapy
Monocyclic 5‐membered heterocycles including imidazoles, thiazoles, oxazoles, and their
related compounds have gained significant attention in medicinal chemistry because of their …
related compounds have gained significant attention in medicinal chemistry because of their …
Novel PPAR-γ agonists as potential neuroprotective agents against Alzheimer's disease: rational design, synthesis, in silico evaluation, PPAR-γ binding assay and …
Alzheimer's disease (AD) is a neurological disorder. It is caused by accumulation of amyloid
beta (Aβ) plaques and tau tangles, which gradually leads to cognitive decline and memory …
beta (Aβ) plaques and tau tangles, which gradually leads to cognitive decline and memory …
Design, synthesis and evaluation of new thiazolidin-4-ones as LPA1 receptor antagonists for breast cancer therapy
Aim: Breast cancer has been a leading cause of mortality among women worldwide in
recent years. Targeting the lysophosphatidic acid (LPA)–LPA1 pathway using small …
recent years. Targeting the lysophosphatidic acid (LPA)–LPA1 pathway using small …